Shares of Ardelyx (NASDAQ: ARDX) surged 14.37% in after-hours trading following the release of the company's third quarter financial results that exceeded analyst expectations and showcased robust growth for its key products.
The biopharmaceutical company reported total revenue of $110.329 million for Q3 2025, beating the analyst consensus estimate of $100.878 million by 9.37%. This represents a significant 12.30% increase compared to sales of $98.241 million in the same period last year. The strong performance was primarily driven by impressive growth in IBSRELA sales and steady progress for XPHOZAH.
IBSRELA, Ardelyx's treatment for irritable bowel syndrome with constipation (IBS-C), generated $78.2 million in Q3 revenue, reflecting a remarkable 92% year-over-year growth. Based on this strong performance, the company raised its full-year 2025 revenue guidance for IBSRELA to between $270-275 million. Meanwhile, XPHOZAH, used to reduce serum phosphorus in adults with chronic kidney disease on dialysis, recorded $27.4 million in Q3 revenue, up 9% compared to Q2 2025. The company also announced progress on a pipeline program for a next-generation NHE3 inhibitor, showcasing potential for future growth across multiple therapeutic areas.