Zions Bancorp (NASDAQ: ZION) stock is experiencing a significant pre-market plunge of 5.27% on Tuesday, following the release of its disappointing first-quarter results and a series of analyst downgrades. The regional bank's performance has raised concerns among investors about its near-term prospects in an uncertain economic environment.

The company reported first-quarter earnings of $1.13 per share, missing analyst estimates of $1.17 per share. Revenue also fell short at $795 million, compared to the expected $797.07 million. In response to these results, several prominent financial institutions have lowered their price targets for Zions Bancorp. Wells Fargo cut its target from $58 to $47, JP Morgan reduced its target from $55 to $50, and RBC lowered its target from $63 to $53, among others.

Adding to investor concerns, Zions Bancorp CEO Harris Simmons highlighted the uncertain economic outlook, citing potential negative impacts from tariffs and trade policies. While the bank's credit quality remained stable, with nonperforming assets at 0.51% of loans and leases, the combination of missed earnings, lowered price targets, and economic uncertainties has led to a significant sell-off in pre-market trading. Investors will be closely watching how the stock performs throughout the trading session and in the coming days as the market digests this news.