HK Stock Movement | JACOBIO-B (01167) Surges Over 6% Intraday as Subsidiary Receives RMB125M Upfront Payment and Combination Therapy Published in The Lancet

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2025/12/04

JACOBIO-B (01167) rose over 6% intraday, with gains narrowing to 5.51% by press time at HK$8.04, recording a turnover of HK$8.15 million. The company announced that its subsidiary, Beijing Jacobio, received an upfront payment of RMB125 million from Oceanpine Capital. This payment strengthens the group's cash reserves and supports further R&D of innovative oncology therapies. Additionally, JACOBIO recently revealed that clinical Phase I/IIa results of its self-developed KRAS G12C inhibitor glecirasib combined with SHP2 inhibitor JAB-3312 (sitneprotafib) were published in The Lancet Respiratory Medicine (impact factor: 32.8). This marks the first global publication of systematic clinical data on dual oral small-molecule combination therapy targeting KRAS G12C and SHP2 in the prestigious journal.

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The company announced that its subsidiary, Beijing Jacobio, received an upfront payment of RMB125 million from Oceanpine Capital. This payment strengthens the group's cash reserves and supports further R&D of innovative oncology therapies. Additionally, JACOBIO recently revealed that clinical Phase I/IIa results of its self-developed KRAS G12C inhibitor glecirasib combined with SHP2 inhibitor JAB-3312 (sitneprotafib) were published in The Lancet Respiratory Medicine (impact factor: 32.8). 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