Avantor, Inc. (AVTR) experienced a significant pre-market plunge of 5.47% following the release of its fourth quarter and full year 2025 financial results.

The company reported a dramatic 89.6% decrease in net income for the quarter, falling to USD 52 million. While quarterly sales of USD 1,663.6 million slightly exceeded analyst estimates, the sharp decline in profitability appears to have driven negative investor sentiment. The earnings release also noted full-year impairment charges of USD 785 million and a 1.4% year-over-year decrease in net sales for the quarter.

Management highlighted the initiation of a business transformation plan, "Revival," aimed at driving growth, describing 2026 as a year of transition and investment.