Space stocks gained in premarket trading with DXYZ up 5%, EchoStar, Virgin Galatic up over 3%; Planet Labs, Redwire up about 2%.

Sanofi’s shares dropped 4% in premarket trading as its experimental multiple sclerosis drug got hit with two setbacks on Monday: a regulatory delay in the US as well as a failure in a late-stage clinical trial.

The US Food and Drug Administration decision on the medicine, called tolebrutinib, to treat an advanced form of multiple sclerosis will likely be delayed, with further guidance from the regulator at the end of the first quarter, the French drugmaker said.