Assembly Biosciences Shares Rise on Results from Hepatitis B Drug Trial

Dow Jones

2024-12-26

By Dean Seal

Shares of Assembly Biosciences advanced after the company reported encouraging results from a clinical trial of its treatment for the hepatitis B virus.

The stock was up 5.2% at $15.49 in premarket trading. Shares have risen 50% since the start of the year.

The biotechnology company said Thursday that in its ongoing Phase 1b study, a 150 milligram dose of ABI-4334 showed strong antiviral activity and a mean reduction in plasma hepatitis B virus DNA over 28 days of treatment.

ABI-4334 was well-tolerated, with a favorable safety profile and a half-life that supports once-daily oral dosing, Assembly said.

Enrollment for a final cohort of patients dosed with 400 milligrams of ABI-4334 is expected in the first half of 2025.

Write to Dean Seal at dean.seal@wsj.com

(END) Dow Jones Newswires

December 26, 2024 09:00 ET (14:00 GMT)

Copyright (c) 2024 Dow Jones & Company, Inc.

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Shares have risen 50% since the start of the year. \n\n\n  The biotechnology company said Thursday that in its ongoing Phase 1b study, a 150 milligram dose of ABI-4334 showed strong antiviral activity and a mean reduction in plasma hepatitis B virus DNA over 28 days of treatment. \n\n\n  ABI-4334 was well-tolerated, with a favorable safety profile and a half-life that supports once-daily oral dosing, Assembly said. \n\n\n  Enrollment for a final cohort of patients dosed with 400 milligrams of ABI-4334 is expected in the first half of 2025. \n\n\n  Write to Dean Seal at dean.seal@wsj.com \n\n\n  (END) Dow Jones Newswires\n\n\n  December 26, 2024 09:00 ET (14:00 GMT)\n\n\n  Copyright (c) 2024 Dow Jones & Company, Inc.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"dataReport","news_rank":0,"symbols":[],"gpt_button":0,"code":"91000000","status":"200"}}}