Press Release: Ginkgo Bioworks Reports First Quarter 2025 Financial Results

Dow Jones
05/07

Ginkgo Bioworks Reports First Quarter 2025 Financial Results

PR Newswire

BOSTON, May 6, 2025

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BOSTON, May 6, 2025 /PRNewswire/ -- Ginkgo Bioworks Holdings, Inc. (NYSE: DNA, "Ginkgo"), which is building the leading platform for cell programming and biosecurity, today announced its results for the first quarter ended March 31, 2025. The update, including a webcast slide presentation with additional details on the first quarter, as well as supplemental financial information will be available at investors.ginkgobioworks.com.

First Quarter 2025 Financial Results

   -- First quarter 2025 Total revenue of $48 million, up from $38 million in 
      the comparable prior year period, an increase of 27% primarily due to $7 
      million of non-cash revenue from the release of deferred revenue relating 
      to the mutual termination of a customer agreement. Excluding this impact, 
      Total revenue in the quarter was $41 million, an increase of 8% over the 
      prior year period. 
 
          -- Excluding the $7 million non-cash deferred revenue release, first 
             quarter 2025 Cell Engineering revenue of $31 million, up from $28 
             million in the comparable prior year period, an increase of 10%, 
             primarily driven by growth with biopharma and government customers 
 
          -- First quarter 2025 Biosecurity revenue of $10 million, flat to $10 
             million in the comparable prior year period 
 
   -- First quarter 2025 GAAP net loss of $(91) million, compared to $(166) 
      million in the comparable prior year period 
 
   -- First quarter 2025 Adjusted EBITDA of $(47) million, up from $(117) 
      million in the comparable prior year period, driven by the increase in 
      revenue as well as a decrease in operating expenses 
 
   -- Cash, cash equivalents and marketable securities balance as of March 31, 
      2025 of $517 million 

"We're starting the year on a solid base thanks to the significant restructuring efforts of the past year," said Jason Kelly, co-founder and CEO of Ginkgo Bioworks. "Our Solutions business has become a trusted R&D service provider to the US Government and biopharma industry, meanwhile our Tools businesses have traction with existing offerings and are positioned to meet emergent opportunities in areas like AI, which are driving demand for large scale biological datasets. Through all of this, we are maintaining our commitment to achieving our cost reduction targets."

Recent Business Highlights & Strategic Positioning

   -- Biotechnology remains a critical emerging technology area in the US and 
      Ginkgo is well positioned to provide biosecurity and R&D services 
 
          -- Office of Science and Technology Policy (OSTP) Director Michael 
             Kratsios and the National Security Commission on Emerging 
             Biotechnology (NSCEB) report have both recently emphasized biotech 
             as an area of national importance 
 
          -- We have 28 US Government projects across Cell Engineering 
             and Biosecurity with $180M of contracted backlog and unfunded 
             potential backlog 
 
   -- Ginkgo's Datapoints and Automation offerings are seeing new deals and 
      opportunities emerging 
 
          -- Datapoints published GDPa1, an antibody developability dataset for 
             246 IgGs across 10 assays, generated using Ginkgo's 
             high-throughput PROPHET-Ab platform 
 
          -- Automation signed a deal recently with Aura Genetics, our first 
             diagnostics company customer 
 
   -- We made progress on our objective to reach Adjusted EBITDA breakeven by 
      the end of 2026 
 
          -- Ginkgo's reduction in force and other cost cutting measures have 
             achieved an annualized run-rate cost reduction of $205 million as 
             of the first quarter of 2025, with a target to achieve $250 
             million in cost reduction by the end of the third quarter of 2025. 
             Site consolidation efforts were substantially completed by the 
             year ended 2024, with excess space available for sublease. 

Full Year 2025 Guidance

   -- Ginkgo previously issued 2025 guidance for Total revenue of $160-$180 
      million, Cell Engineering revenue of $110-$130 million; and Biosecurity 
      revenue of at least $50 million.  Ginkgo updates its previously issued 
      guidance solely to reflect the impact of the previously mentioned $7 
      million non-cash deferred revenue release in the first quarter to: 
 
          -- Total revenue of $167-$187 million in 2025; 
 
          -- Cell engineering revenue of $117-$137 million in 2025; and 
 
          -- Biosecurity revenue of at least $50 million in 2025. 

Conference Call Details

Ginkgo will host a videoconference today, Tuesday, May 6, 2025, beginning at 5:30 p.m. ET. The presentation will include an overview of the first quarter of 2025, recent business updates, a discussion on Ginkgo's outlook, as well as a moderated question and answer session.

To ask a question ahead of the presentation, please submit your questions to @Ginkgo on X (hashtag #GinkgoResults) or by sending an e-mail to investors@ginkgobioworks.com.

A webcast link is available on Ginkgo's Investor Relations website and a replay will be made available following the presentation.

Ginkgo Investor Website: https://investors.ginkgobioworks.com/events/

Audio-Only Dial Ins:

+1 646 931 3860 (New York)

+1 301 715 8592 (Washington DC)

+1 305 224 1968 (Miami)

+1 312 626 6799 (Chicago)

+1 346 248 7799 (Houston)

+1 408 638 0968 (San Jose)

+1 564 217 2000 (Seattle)

+1 689 278 1000 (Orlando)

Webinar ID: 966 5095 4269

If you experience technical difficulties with any of these dial-ins or if you need international dial-in numbers, please visit our website at https://investors.ginkgobioworks.com/events/ for updated dial-in information.

About Ginkgo Bioworks

Ginkgo Bioworks is the leading horizontal platform for cell programming, providing flexible, end-to-end services that solve challenges for organizations across diverse markets, from food and agriculture to pharmaceuticals to industrial and specialty chemicals. Ginkgo Biosecurity is building and deploying the next-generation infrastructure and technologies that global leaders need to predict, detect, and respond to a wide variety of biological threats. For more information, visit ginkgobioworks.com and ginkgobiosecurity.com, read our blog, or follow us on social media channels such as X (@Ginkgo and @Ginkgo_Biosec), Instagram (@GinkgoBioworks), Threads (@GinkgoBioworks) or LinkedIn.

Forward-Looking Statements of Ginkgo Bioworks

This press release, the presentation, and the conference call and webcast contain certain forward-looking statements within the meaning of the federal securities laws, including statements regarding our plans, strategies, including with respect to our current expectations, operations and anticipated results of operations, both business and financial, including the timing for attaining Adjusted EBITDA breakeven, impacts of our restructuring, potential customer success, including successful application of our offerings by our customers, the regulatory landscape, and expectations with regard to revenue, including our ability to meet all milestones and achieve the maximum revenue available under certain of our customer arrangements, expenses, our full year 2025 outlook, and the market environment, all of which are subject to known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements, market trends, or industry results to differ materially from those expressed or implied by such forward-looking statements. These forward-looking statements generally are identified by the words "believe," "can," "project," "potential," "expect," "anticipate," "estimate," "intend," "strategy," "future," "opportunity," "plan," "may," "should," "will," "would," "will be," "will continue," "will likely result," and similar expressions. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this document, including but not limited to: (i) our ability to realize near-term and long-term cost savings associated with our site consolidation plans, including the ability to terminate leases or find sub-lease tenants for unused facilities, (ii) volatility in the price of Ginkgo's securities due to a variety of factors, including changes in the competitive and highly regulated industries in which Ginkgo operates and plans to operate, variations in performance across competitors, and changes in laws and regulations affecting Ginkgo's business, (iii) the ability to implement business plans, forecasts, and other expectations, and to identify and realize additional business opportunities, including with respect to our solutions and tools offerings, (iv) the risk of downturns in demand for products using synthetic biology, (v) the uncertainty regarding the demand for passive monitoring programs and biosecurity services, (vi) changes to the biosecurity industry, including due to advancements in technology, emerging competition and evolution in industry demands, standards and regulations, (vii) the outcome of any pending or potential legal proceedings against Ginkgo, (viii) our ability to realize the expected benefits from and the success of our Foundry platform programs and Codebase assets, (ix) our ability to successfully develop

engineered cells, bioprocesses, data packages or other deliverables, (x) the product development, production or manufacturing success of our customers, (xi) our exposure to the volatility and liquidity risks inherent in holding equity interests in other operating companies and other non-cash consideration we may receive for our services, (xii) the potential negative impact on our business of our restructuring or the failure to realize the anticipated savings associated therewith and (xiii) the uncertainty regarding government budgetary priorities and funding allocated to government agencies. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the "Risk Factors" section of Ginkgo's annual report on Form 10-K filed with the U.S. Securities and Exchange Commission (the "SEC") on February 25, 2025 and other documents filed by Ginkgo from time to time with the SEC. These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and Ginkgo assumes no obligation to update or revise these forward-looking statements, whether as a result of new information, future events, or otherwise. Ginkgo does not give any assurance that it will achieve its expectations.

Use of Non-GAAP Financial Measures

Certain of the financial measures included in this release, including Adjusted EBITDA, have not been prepared in accordance with generally accepted accounting principles ("GAAP"), and constitute "non-GAAP financial measures" as defined by the SEC. Ginkgo has included these non-GAAP financial measures because it believes they provide an additional tool for investors to use in evaluating Ginkgo's financial performance and prospects. Due to the nature and/or size of the items being excluded, such items do not reflect future gains, losses, expenses or benefits and are not indicative of our future operating performance. These non-GAAP financial measures are supplemental to, and should not be considered in isolation from, or as an alternative to, financial measures determined in accordance with GAAP. In addition, these non-GAAP financial measures may differ from non-GAAP financial measures with comparable names used by other companies. See the reconciliation below for additional information regarding certain of the non-GAAP financial measures included in this release, including a description of these non-GAAP financial measures and a reconciliation of the historic measures to Ginkgo's most comparable GAAP financial measures.

Ginkgo Bioworks Contacts:

INVESTOR CONTACT:

investors@ginkgobioworks.com

MEDIA CONTACT:

press@ginkgobioworks.com

 
                       Ginkgo Bioworks Holdings, Inc. 
                    Condensed Consolidated Balance Sheets 
                                 (unaudited) 
                      (in thousands, except share data) 
                                 As of March 31,        As of December 31, 
                              ----------------------  ---------------------- 
                                       2025                    2024 
                              ----------------------  ---------------------- 
Assets 
Current assets: 
Cash and cash equivalents      $             312,420   $             561,572 
Marketable securities                        204,502                      -- 
Accounts receivable, net                      26,293                  21,857 
Accounts receivable - 
 related parties                                 877                     586 
Prepaid expenses and other 
 current assets                               20,442                  18,729 
                              ----------------------  ---------------------- 
Total current assets                         564,534                 602,744 
Property, plant and 
 equipment, net                              197,828                 203,720 
Operating lease right-of-use 
 assets                                      383,394                 394,435 
Investments                                   32,173                  48,704 
Intangible assets, net                        68,756                  72,510 
Other non-current assets                      46,778                  55,336 
                              ----------------------  ---------------------- 
Total assets                    $          1,293,463    $          1,377,449 
                              ----------------------  ---------------------- 
Liabilities and 
Stockholders' Equity 
Current liabilities: 
Accounts payable              $               11,267  $               14,169 
Deferred revenue                              33,653                  27,710 
Accrued expenses and other 
 current liabilities                          70,747                  65,387 
                              ----------------------  ---------------------- 
Total current liabilities                    115,667                 107,266 
Non-current liabilities: 
Deferred revenue, net of 
 current portion                              80,378                  98,783 
Operating lease liabilities, 
 non-current                                 434,561                 438,766 
Other non-current 
 liabilities                                  15,430                  16,576 
                              ----------------------  ---------------------- 
Total liabilities                            646,036                 661,391 
                              ----------------------  ---------------------- 
Commitments and 
contingencies 
Stockholders' equity: 
Preferred stock, $0.0001 par 
value                                             --                      -- 
Common stock, $0.0001 par 
 value                                             5                       5 
Additional paid-in capital                 6,576,786               6,555,416 
Accumulated deficit                      (5,928,514)             (5,837,557) 
Accumulated other 
 comprehensive loss                            (850)                 (1,806) 
                              ----------------------  ---------------------- 
Total stockholders' equity                   647,427                 716,058 
                              ----------------------  ---------------------- 
Total liabilities and 
 stockholders' equity           $          1,293,463    $          1,377,449 
                              ----------------------  ---------------------- 
 
 
                       Ginkgo Bioworks Holdings, Inc. 
   Condensed Consolidated Statements of Operations and Comprehensive Loss 
                                 (unaudited) 
                      (in thousands, except share data) 
                                         Three Months Ended March 31, 
                                  ------------------------------------------ 
                                          2025                  2024 
                                  --------------------  -------------------- 
Cell Engineering revenue             $          38,230     $          27,889 
Biosecurity revenue                             10,088                10,055 
                                  --------------------  -------------------- 
Total revenue                                   48,318                37,944 
                                  --------------------  -------------------- 
Costs and operating expenses: 
 Cost of Biosecurity revenue (1)                 7,957                 9,202 
 Cost of other revenue (1)                       4,090                    -- 
Research and development (1)                    70,923               136,457 
General and administrative (1)                  49,043                70,287 
Restructuring charges                            5,273                    -- 
                                  --------------------  -------------------- 
Total operating expenses                       137,286               215,946 
                                  --------------------  -------------------- 
Loss from operations                          (88,968)             (178,002) 
Other income (expense): 
 Interest income, net                            6,081                11,711 
 Loss on investments                           (3,693)               (2,544) 
 Change in fair value of warrant 
  liabilities                                       --                   940 
 Other income (expense), net                   (4,289)                 2,015 
                                  --------------------  -------------------- 
Total other income (expense)                   (1,901)                12,122 
                                  --------------------  -------------------- 
Loss before income taxes                      (90,869)             (165,880) 
Income tax expense                                  88                    31 
                                  --------------------  -------------------- 
Net loss                            $         (90,957)      $      (165,911) 
                                  --------------------  -------------------- 
Net loss per share: 
 Basic                            $             (1.68)  $             (3.31) 
 Diluted                          $             (1.68)  $             (3.32) 
Weighted average common shares 
outstanding: 
 Basic                                      54,241,619            50,111,460 
 Diluted                                    54,241,619            50,133,366 
Comprehensive loss: 
 Net loss                           $         (90,957)      $      (165,911) 
Other comprehensive (loss) 
income: 
 Foreign currency translation 
  adjustment                                       849               (3,035) 
 Unrealized gains on 
 available-for-sale securities                     107                    -- 
                                  --------------------  -------------------- 
Total other comprehensive (loss) 
 income                                            956               (3,035) 
                                  --------------------  -------------------- 
Comprehensive loss                  $         (90,001)      $      (168,946) 
                                  --------------------  -------------------- 
 
 
 
(1)    Total stock-based compensation expense, inclusive of employer payroll 
taxes, was allocated as follows (in thousands): 
 
 
 
                                   Three Months Ended March 31, 
                              -------------------------------------- 
                                     2025                2024 
                              -------------------  ----------------- 
Research and development      $             9,184  $          24,120 
General and administrative                  9,912             18,277 
Cost of Biosecurity revenue                   735                 -- 
Cost of other revenue                         969                 -- 
                              -------------------  ----------------- 
Total                           $          20,800  $          42,397 
                              -------------------  ----------------- 
 
 
                       Ginkgo Bioworks Holdings, Inc. 
               Condensed Consolidated Statements of Cash Flows 
                                 (unaudited) 
                               (in thousands) 
                                            Three Months Ended March 31, 
                                        ------------------------------------ 
                                              2025               2024 
                                        -----------------  ----------------- 
Cash flows from operating activities: 
Net loss                                $        (90,957)   $      (165,911) 
Adjustments to reconcile net loss to net cash used in operating activities: 
 Depreciation and amortization                     15,366             12,869 
 Stock-based compensation                          20,431             40,782 
 Loss on investments                                3,693              2,544 
 Change in fair value of notes 
 receivable                                         5,285                 -- 
 Change in fair value of warrant 
  liabilities                                          --              (940) 
 Change in fair value of contingent 
  consideration                                   (1,302)              (926) 
 Non-cash lease expense                             7,379              5,637 
 Non-cash in-process research and 
  development                                          --             16,816 
 Other non-cash activity                              149              (442) 
Changes in operating assets and 
liabilities: 
 Accounts receivable                              (4,693)            (6,770) 
 Prepaid expenses and other current 
  assets                                              462              1,154 
 Operating lease right-of-use assets                3,675                 -- 
 Other non-current assets                           (167)              (707) 
 Accounts payable, accrued expenses 
  and other current liabilities                     6,419             10,871 
 Deferred revenue, current and 
  non-current                                    (12,471)            (2,912) 
 Operating lease liabilities, current 
  and non-current                                 (4,790)            (4,097) 
 Other non-current liabilities                         --              2,773 
                                        -----------------  ----------------- 
Net cash used in operating activities            (51,521)           (89,259) 
                                        -----------------  ----------------- 
Cash flows from investing activities: 
Purchases of marketable debt 
securities                                      (191,182)                 -- 
Purchases of property and equipment               (7,622)            (6,710) 
Business acquisition                                   --            (5,400) 
Other                                                 120                 -- 
                                        -----------------  ----------------- 
Net cash used in investing activities           (198,684)           (12,110) 
                                        -----------------  ----------------- 
Cash flows from financing activities: 
Proceeds from exercise of stock 
 options                                               --                 70 
Principal payments on finance leases                (207)              (294) 
Contingent consideration payment                       --              (621) 
                                        -----------------  ----------------- 
Net cash used in financing activities               (207)              (845) 
                                        -----------------  ----------------- 
Effect of foreign exchange rates on 
 cash and cash equivalents                             74              (157) 
                                        -----------------  ----------------- 
Net decrease in cash, cash equivalents 
 and restricted cash                            (250,338)          (102,371) 
 
Cash and cash equivalents, beginning 
 of period                                        561,572            944,073 
Restricted cash, beginning of period               44,171             45,511 
                                        -----------------  ----------------- 
Cash, cash equivalents and restricted 
 cash, beginning of period                        605,743            989,584 
 
Cash and cash equivalents, end of 
 period                                           312,420            840,440 
Restricted cash, end of period                     42,985             46,773 
                                        -----------------  ----------------- 
Cash, cash equivalents and restricted 
 cash, end of period                    $         355,405  $         887,213 
                                        -----------------  ----------------- 
 
 
                       Ginkgo Bioworks Holdings, Inc. 
                            Segment Information 
                         (in thousands, unaudited) 
 
                                       Three Months Ended March 31, 
                              ---------------------------------------------- 
                                       2025                    2024 
                              ----------------------  ---------------------- 
Cell Engineering 
Revenue                       $               38,230  $               27,889 
Costs and operating 
expenses: 
  Cost of other revenue                        3,121                      -- 
  Research and development                    48,670                  81,898 
  General and administrative                  18,027                  38,244 
                              ----------------------  ---------------------- 
Cell Engineering operating 
 loss                                       (31,588)                (92,253) 
                              ----------------------  ---------------------- 
Biosecurity 
Revenue                                       10,088                  10,055 
Costs and operating 
expenses: 
  Cost of Biosecurity 
   revenue                                     7,223                   9,202 
  Research and development                        --                     120 
  General and administrative                   8,050                  11,951 
                              ----------------------  ---------------------- 
Biosecurity operating loss                   (5,185)                (11,218) 
                              ----------------------  ---------------------- 
Total segment operating loss                (36,773)               (103,471) 
                              ----------------------  ---------------------- 
Reconciling items to reconcile total segment operating loss to loss before 
income taxes: 
Stock-based compensation (1)                  20,800                  42,397 
Depreciation and 
 amortization                                 15,366                  12,869 
Restructuring charges (2)                      5,273                      -- 
Carrying cost of excess 
space (net of sublease 
income) (3)                                   11,674                      -- 
Merger and acquisition 
 related expense (income) 
 (4)                                           (918)                   2,394 
Acquired in-process research 
 and development                                  --                  16,871 
Other (income) expense, net 
 (5)                                           1,901                (12,122) 
                              ----------------------  ---------------------- 
Loss before income taxes      $             (90,869)   $           (165,880) 
                              ----------------------  ---------------------- 
 
 
 
(1)  Includes $0.4 million and $1.6 million in employer payroll taxes for the 
     three months ended March 31, 2025 and 2024, respectively. 
 
(2)  Restructuring charges primarily consist of employee termination costs 
     from the reduction in force commenced in June 2024. 
 
(3)  The carrying cost of excess space includes base rent, common area 
     maintenance charges, and real estate taxes associated with facilities the 
     Company is not occupying, net of any sublease income from these spaces. 
 
(4)  Represents transaction and integration costs directly related to mergers 
     and acquisitions, including: (i) legal, consulting, and accounting fees 
     associated with acquisitions; (ii) post-acquisition employee retention 
     bonuses; (iii) (gain)/loss from changes in the fair value of contingent 
     consideration liabilities resulting from acquisitions; and (iv) costs 
     associated with the Zymergen Bankruptcy, as well as securities litigation 
     costs. 
 
(5)  Includes interest income, interest expense, loss on investments, changes 
     in fair value of certain assets and liabilities, and other gains and 
     losses. 
 
 
                       Ginkgo Bioworks Holdings, Inc. 
                    Selected Non-GAAP Financial Measures 
                         (in thousands, unaudited) 
 
                                            Three Months Ended March 31, 
                                        ------------------------------------ 
(in thousands)                                 2025               2024 
                                        ------------------  ---------------- 
Net loss (1)                            $         (90,957)  $      (165,911) 
Interest income, net                               (6,081)          (11,711) 
Income tax expense                                      88                31 
Depreciation and amortization                       15,366            12,869 
                                        ------------------  ---------------- 
EBITDA                                            (81,584)         (164,722) 
Stock-based compensation (2)                        20,800            42,397 
Restructuring charges (3)                            5,273                -- 
Loss on investments                                  3,693             2,544 
Change in fair value of warrant 
 liabilities                                            --             (940) 
Merger and acquisition related expense 
 (income) (4)                                        (918)             2,394 
Change in fair value of convertible 
 notes                                               5,285             1,326 
                                        ------------------  ---------------- 
Adjusted EBITDA                         $         (47,451)  $      (117,001) 
                                        ------------------  ---------------- 
 
 
 
(1)  All periods include non-cash revenue when earned, including $7.5 million 
     in the three months ended March 31, 2025 recognized pursuant to the 
     termination of revenue contracts with BiomEdit. 
 
(2)  Includes $0.4 million and $1.6 million in employer payroll taxes for the 
     three months ended March 31, 2025 and 2024, respectively. 
 
(3)  Restructuring charges primarily consist of employee termination costs 
     from the reduction in force commenced in June 2024. 
 
(4)  Represents transaction and integration costs directly related to mergers 
     and acquisitions, including: (i) legal, consulting, and accounting fees 
     associated with acquisitions; (ii) post-acquisition employee retention 
     bonuses; (iii) (gain)/loss from changes in the fair value of contingent 
     consideration liabilities resulting from acquisitions; and (iv) costs 
     associated with the Zymergen Bankruptcy, as well as securities litigation 
     costs. Not included in this adjustment are acquired in-process research 
     and development expenses, which totaled zero and $16.9 million for the 
     three months ended March 31, 2025 and 2024, respectively. 
 

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