Ascentage Pharma Group International has recently announced the submission of a new drug application for lisaftoclax in China, marking a significant milestone in the program's progress. This novel Bcl-2 inhibitor has demonstrated antitumor activity in both previously untreated patients and those treated with venetoclax, addressing critical treatment gaps in difficult-to-treat myeloid malignancies. If approved, lisaftoclax would be the second Bcl-2 inhibitor to receive approval globally. This regulatory submission underscores Ascentage Pharma's commitment to developing innovative therapies for patients with limited treatment options.
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