Arcus Biosciences Announces Promising Initial Data for Casdatifan Plus Cabozantinib in Metastatic Kidney Cancer, Prepares to Launch Phase 3 PEAK-1 Study

Reuters

06-01

Arcus Biosciences Announces Promising Initial Data for Casdatifan Plus Cabozantinib in Metastatic Kidney Cancer, Prepares to Launch Phase 3 PEAK-1 Study

Arcus Biosciences Inc. has announced initial data from the ARC-20 study, which evaluated the combination of casdatifan and cabozantinib in patients with metastatic kidney cancer. The study reported a confirmed overall response rate of 46% in patients who had at least 12 weeks of follow-up. The combination therapy was well-tolerated and demonstrated a manageable safety profile, with no significant overlapping toxicity between the drugs. These findings support the launch of two new studies: PEAK-1, a Phase 3 trial for immunotherapy-experienced clear cell renal cell carcinoma (ccRCC) patients, and eVOLVE-RCC02, a Phase 1b/3 trial for first-line ccRCC patients. Arcus Biosciences will discuss these data further in a conference call scheduled for June 2, 2025.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Arcus Biosciences Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20250601016939) on June 01, 2025, and is solely responsible for the information contained therein.

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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Arcus Biosciences Inc. published the original content used to generate this news brief via Business Wire (Ref. 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