Biogen Inc. Announces Promising Phase 3 Trial Results for Dapirolizumab Pegol in Treating Systemic Lupus Erythematosus

Reuters
2025/06/12
Biogen Inc. Announces Promising Phase 3 Trial Results for Dapirolizumab Pegol in Treating Systemic Lupus Erythematosus

BRUSSELS and CAMBRIDGE, Mass., June 12, 2025 (GLOBE NEWSWIRE) -- Biogen Inc. $(BIIB)$ and UCB have announced the presentation of additional detailed results from their Phase 3 PHOENYCS GO study at the European Alliance of Associations for Rheumatology's annual meeting (EULAR 2025) in Barcelona, Spain. The study evaluates dapirolizumab pegol (DZP), a novel Fc-free anti-CD40L drug candidate, in patients with moderate-to-severe systemic lupus erythematosus $(SLE)$. The results demonstrated significant clinical improvements in disease activity, including fatigue and disease activity/remission, as measured by the British Isles Lupus Assessment Group (BILAG)-based Composite Lupus Assessment (BICLA) at Week 48, the primary endpoint. Dapirolizumab pegol is not yet approved for use in SLE by any regulatory authority, and a second Phase 3 trial is ongoing to confirm these findings.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Biogen Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9467293-en) on June 12, 2025, and is solely responsible for the information contained therein.

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