Cabaletta Bio, Inc. (Nasdaq: CABA), a clinical-stage biotechnology company, has announced new clinical and translational data from its ongoing RESET-Myositis™, RESET-SLE™, and RESET-SSc™ trials. These trials are evaluating the efficacy of rese-cel (resecabtagene autoleucel) in treating autoimmune diseases. The data, based on 18 evaluable patients, are being presented at the European Alliance of Associations for Rheumatology (EULAR) 2025 Congress in Barcelona, Spain, held from June 11-14, 2025. Key findings include clinically meaningful responses in myositis patients, remission in SLE patients without nephropathy, and improvement in scleroderma patients, with most patients off immunomodulators and steroids. Safety data indicate a low incidence of CRS and ICANS. Cabaletta Bio plans to engage with the FDA on registrational program designs for various indications to advance the development of rese-cel as a targeted curative cell therapy for autoimmune diseases.
免责声明:投资有风险,本文并非投资建议,以上内容不应被视为任何金融产品的购买或出售要约、建议或邀请,作者或其他用户的任何相关讨论、评论或帖子也不应被视为此类内容。本文仅供一般参考,不考虑您的个人投资目标、财务状况或需求。TTM对信息的准确性和完整性不承担任何责任或保证,投资者应自行研究并在投资前寻求专业建议。