Nxera Pharma Co. Ltd. has announced that it will receive US$4.8 million in milestone payments from Centessa Pharmaceuticals. This follows the initiation of clinical development of ORX142, a novel Orexin Receptor 2 (OX2R) agonist. This development comes after the recent clearance of an Investigational New Drug $(IND.AU)$ application by the US Food and Drug Administration (FDA) for a Phase 1 clinical study of ORX142 in healthy volunteers. ORX142 is being developed for the treatment of select neurological and neurodegenerative disorders. Of the milestone payments, US$1.8 million will be recognized as revenue in the second quarter of 2025, while the remaining US$3.0 million will be recognized in the third quarter of 2025. The results of the study have not yet been presented.