US stocks look set to open lower in Wednesday's trading session as key employment data missed analyst forecasts.

The Dow Jones Industrial Average futures were off 0.1%, S&P 500 futures were down 0.2%, and Nasdaq futures declined 0.4%.

Oil prices were moving higher, with front-month global benchmarks Brent crude and West Texas Intermediate crude rising 1.1% and 1.2% respectively.

In other world markets, Japan's Nikkei declined 0.6%, Hong Kong's Hang Seng gained 0.6%, and China's Shanghai Composite edged 0.1% lower. Meanwhile in Europe's early afternoon session, the UK's FTSE 100 was off 0.2%, while Germany's DAX was unchanged and France's CAC 40 rose 0.9%.

The ADP National Employment Report, which gauges the monthly change in non-farm, private employment, reported a 33,000 decrease in June, compared with a 29,000 gain in May and missing analyst expectations for a 99,000 increase, according to Bloomberg.

Later in the morning, the Energy Information Administration's weekly crude oil inventories report will be released. The change in the number of barrels of commercial crude oil held by US firms could be an indicator of inflation direction. Analysts are expecting a decrease of 3.5 million barrels, compared with a 5.8 million barrel decrease the previous week.

In equities, shares of Mogo (MOGO) soared 208% in Wednesday's premarket session after it said its board has authorized allocating up to $50 million to bitcoin as part of its long-term capital preservation strategy. CID (DAIC) jumped 90% after a 10% loss the previous session. Earlyworks (ELWS) jumped 50%, adding to a 6% gain from Tuesday. Globavend (GVH) surged 30%, erasing much of the previous session's 42% loss. And shares of Perfect Moment (PMNT) advanced 16% after a 14% loss on Tuesday.

On the losing side, shares of BioNexus Gene Lab (BGLC) tumbled 45% after soaring 256% in the previous session. Curis (CRIS) shed 32% after it said Tuesday it launched a $7 million registered direct offering and private placement. Shares of Centene (CNC) dropped 31% after the health insurer withdrew its full-year 2025 earnings outlook due to lower-than-expected revenue. Mustang Bio's (MBIO) stock fell 32% after advancing 115% on Tuesday. And RedCloud's (RCT) stock declined 29% after climbing 43% on Tuesday.