Plus Therapeutics Inc. has announced a change in its certifying accountants, dismissing BDO USA, P.C. as its independent registered public accounting firm. This decision, made by the company's audit committee on July 16, 2025, follows BDO's audit reports for 2023 and 2024, which expressed substantial doubt about Plus Therapeutics' ability to continue as a going concern. The reports contained no adverse opinions, but highlighted a material weakness in internal control over financial reporting, specifically related to the application of appropriate accounting principles for significant and unusual grant revenue transactions as of December 31, 2023. Plus Therapeutics has confirmed that there were no disagreements with BDO on accounting principles, financial statement disclosure, or auditing procedures, and has authorized BDO to address inquiries from their new accounting firm, CBIZ CPAs P.C.