Harbour BioMed has announced the initiation of the POLARIS clinical study, a global, randomized, double-blind, placebo-controlled Phase 2 trial evaluating the dosing, safety, and efficacy of HBM9378/WIN378 in patients with asthma. This trial, conducted in partnership with Windward Bio AG, aims to assess the potential of HBM9378/WIN378 as a long-acting, fully human anti-TSLP antibody with twice-yearly dosing. Initial data from the study are expected to be available in mid-2026. Additionally, HBM9378/WIN378 is being prepared for clinical trials in COPD, with a global program set to commence in mid-2026. The development of HBM9378/WIN378 underscores its potential to address significant unmet needs in treating advanced respiratory diseases.
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