AngioDynamics Inc. has announced the enrollment of the first patient in the AMBITION BTK trial, a prospective, multicenter, randomized controlled trial $(RCT)$ aimed at evaluating the clinical safety and effectiveness of the Auryon Atherectomy System when used in combination with standard balloon angioplasty. This trial focuses on treating infrapopliteal lesions in patients with Critical Limb Ischemia $(CLI.UK)$, a condition with a significant risk of limb loss if untreated. The trial will involve up to 224 patients across 30 sites, with results to be presented in the future. A companion registry will also enroll up to 1,500 additional patients who are ineligible for the RCT. Further information about the study can be found on AngioDynamics' website and ClinicalTrials.gov.