Nautilus Biotechnology Inc. $(NAUT)$ reported its financial results for the second quarter of 2025. The company achieved a net loss of $15.0 million, an improvement from the $18.0 million net loss in the same quarter of the previous year. Operating expenses decreased by 18% to $17.1 million, down from $20.8 million in the prior year period, driven by efforts in cost optimization and reduced expenses in salaries, benefits, stock-based compensation, and professional services. Nautilus Biotechnology's cash, cash equivalents, and investments totaled $179.5 million as of June 30, 2025. The company highlighted significant progress in its proteome analysis platform, including sharing a scientific manuscript that introduces and validates their Iterative Mapping method. Additionally, Nautilus announced collaborations with major research institutes to further explore Alzheimer's disease through their platform and Tau proteoform assay.