Alnylam Pharmaceuticals Unveils Promising New Data from Hypertension and ATTR Program Trials at ESC Congress 2025

Reuters

08/11

Alnylam Pharmaceuticals Unveils Promising New Data from Hypertension and ATTR Program Trials at ESC Congress 2025

Alnylam Pharmaceuticals Inc. has announced the presentation of new data from its hypertension and transthyretin amyloidosis (ATTR) programs at the European Society of Cardiology Congress 2025, scheduled to take place in Madrid, Spain, from August 29 to September 1, 2025. The company will present findings from Cohort A of the KARDIA-3 Phase 2 study, which evaluates the investigational RNAi therapeutic, zilebesiran, for patients with uncontrolled hypertension and high cardiovascular risk. These results will be part of a late-breaking abstract in the Hot Line 4 session on August 30, 2025. Additionally, Alnylam will share data from the HELIOS-B Phase 3 study of AMVUTTRA® (vutrisiran), focusing on its impact on transthyretin amyloidosis with cardiomyopathy (ATTR-CM), including 12-month follow-up results and effects on days lost to death and/or hospitalization. The presentations aim to highlight the potential of RNAi therapeutics in transforming cardiovascular disease treatment.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Alnylam Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20250811966575) on August 11, 2025, and is solely responsible for the information contained therein.

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The company will present findings from Cohort A of the KARDIA-3 Phase 2 study, which evaluates the investigational RNAi therapeutic, zilebesiran, for patients with uncontrolled hypertension and high cardiovascular risk. These results will be part of a late-breaking abstract in the Hot Line 4 session on August 30, 2025. Additionally, Alnylam will share data from the HELIOS-B Phase 3 study of AMVUTTRA® (vutrisiran), focusing on its impact on transthyretin amyloidosis with cardiomyopathy (ATTR-CM), including 12-month follow-up results and effects on days lost to death and/or hospitalization. The presentations aim to highlight the potential of RNAi therapeutics in transforming cardiovascular disease treatment.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Alnylam Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20250811966575) on August 11, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"LU0320765992.SGD","symbol_name":"FTIF - Franklin Biotechnology Discovery A Acc SGD","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250811:nNDL10cbBx:1","article_id":"2558106650","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2558106650","pubTimestamp":1754913776,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Alnylam Pharmaceuticals Inc. has announced the presentation of new data from its hypertension and transthyretin amyloidosis  programs at the European Society of Cardiology Congress 2025, scheduled to take place in Madrid, Spain, from August 29 to September 1, 2025. 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The company will present findings from Cohort A of the KARDIA-3 Phase 2 study, which evaluates the investigational RNAi therapeutic, zilebesiran, for patients with uncontrolled hypertension and high cardiovascular risk. These results will be part of a late-breaking abstract in the Hot Line 4 session on August 30, 2025. Additionally, Alnylam will share data from the HELIOS-B Phase 3 study of AMVUTTRA® (vutrisiran), focusing on its impact on transthyretin amyloidosis with cardiomyopathy (ATTR-CM), including 12-month follow-up results and effects on days lost to death and/or hospitalization. The presentations aim to highlight the potential of RNAi therapeutics in transforming cardiovascular disease treatment.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. 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