Invivyd Inc. has announced new positive in vitro neutralization data for its investigational monoclonal antibodies, PEMGARDA® (pemivibart) and VYD2311, against the currently dominant XFG variant of SARS-CoV-2. These results demonstrate that both antibodies maintain their neutralizing activity, confirming the stability of the epitopes they target. Invivyd's data also show consistent efficacy against other circulating variants, such as NB.1.8.1 ("Nimbus"), LF.7.9, and LP.8.1. The company plans to provide this data to the U.S. Food and Drug Administration (FDA) imminently, with the expectation that it will be included in the PEMGARDA Fact Sheet for Healthcare Providers. The results underscore the potential of Invivyd's antibodies to offer continued clinical activity against evolving SARS-CoV-2 variants.