Wall Street's main indexes declined on Wednesday and the Nasdaq hit a two-week low as a rally in technology stocks cooled and caution prevailed ahead of the Federal Reserve's highly anticipated Jackson Hole symposium later this week. .N

At 11:30 EDT, the Dow Jones Industrial Average .DJI was up 0.09% at 44,963.13. The S&P 500 .SPX was down 0.51% at 6,378.51, and the Nasdaq Composite .IXIC was down 1.10% at 21,080.58.

The top three S&P 500 .PG.INX percentage gainers:

** Regeneron Pharmaceuticals Inc REGN.O, up 3.9%

** Analog Devices Inc ADI.O, up 3.8%

** Medtronic PLC MDT.N, up 3.8%

The top three S&P 500 .PL.INX percentage losers:

** Target Corp TGT.N, down 7.7%

** Intel Corp INTC.O, down 6.3%

** Palantir Technologies Inc PLTR.O, down 5.4%

The top three NYSE .PG.N percentage gainers:

** Guess? Inc GES.N, up 25.7%

** Studio City International Holdings Ltd MSC.N, up 22.3%

** Aspen Insurance Holdings Ltd AHL.N, up 16.4%

The top three NYSE .PL.N percentage losers:

** James Hardie Industries PLC JHX.N, down 35.2%

** PSQ Holdings Inc PSQH.N, down 18.5%

** La-Z-Boy Inc LZB.N, down 13.8%

The top three Nasdaq .PG.O percentage gainers:

** Tharimmune Inc THAR.O, up 141.8%

** Upland Software Inc UPLD.O, up 32.6%

** Shineco Inc SISI.O, up 28.2%

The top three Nasdaq .PL.O percentage losers:

** eLong Power Holding Ltd ELPW.O, down 85.6%

** enVVeno Medical Corp NVNO.O, down 70.2%

** Zeta Network Group ADD.O, down 38.2%

** La-Z-Boy Inc <LZB.N>:BUZZ - Plunges on downbeat quarterly sales forecast nL4N3UC0JP

** ALT5 Sigma Corp <ALTS.O>:BUZZ - Regains some ground after Tuesday's slide nL6N3UC0EE

** Lowe's Companies Inc <LOW.N>:BUZZ - Rises on $8.8 billion deal to buy Foundation Building Materials, upbeat forecast nL6N3UC0EZ

** enCore Energy Corp <EU.O>:BUZZ - Falls after upsized $100 mln convertible debt sale nL6N3UC0EV

** Target Corp <TGT.N>:BUZZ - Down after reaffirming annual forecast despite upbeat Q2 results; names new CEO nL6N3UC0KC

** Estee Laude Companies Inc <EL.N>:BUZZ - Falls after forecasting annual profit below estimates nL6N3UC0FH

** Custom Truck One Source Inc <CTOS.N>:BUZZ - Dips after JPM downgrade nL6N3UC0EB

** Nu Holdings Ltd <NU.N>:BUZZ - Rises after Citigroup double upgrades to 'buy' nL4N3UC0OU

** Toll Brothers Inc <TOL.N>:BUZZ - Falls after mixed Q3 results nL4N3UC0QI

** Figma Inc <FIG.N>:BUZZ - Rises as Piper Sandler starts coverage with 'overweight' rating nL4N3UC0R0

** Rocket Pharmaceuticals Inc <RCKT.O>:BUZZ - Rises after FDA lifts clinical hold on gene therapy trial nL6N3UC0GO

** Dayforce Inc <DAY.N>:BUZZ - Rises on advanced talks for $11 bln deal with Thoma Brava nL4N3UC0TP

** Gap Inc <GAP.N>:BUZZ - Shares dip as Citigroup downgrades stock to 'neutral' on tariff worries nL6N3UC0E2

** Jiayin Group Inc <JFIN.O>:BUZZ - Dips after Q2 costs surge nL4N3UC0T4

** Hertz Global Holdings Inc <HTZ.O>:BUZZ - Rises on Amazon Autos partnership to sell used vehicles online nL4N3UC0UG

** Analog Devices Inc <ADI.O>:BUZZ - Rises on upbeat Q4 outlook, Q3 results beat nL4N3UC0ZH

** TJX Companies Inc <TJX.N>:BUZZ - Hits record high after raising annual profit forecast nL6N3UC0KK

** Guess Inc <GES.N>:BUZZ - Surges on $1.4 billion take-private deal nL6N3UC0K8

** Snowflake Inc <SNOW.N>:BUZZ - Climbs after BofA turns bullish ahead of earnings nL6N3UC0IV

** National Energy Services Reunited Corp <NESR.O>:BUZZ - Up 8% as Q2 results beat estimates nL4N3UC0YE

** Celldex Therapeutics Inc <CLDX.O>:BUZZ - Tumbles after halting development of esophagus drug nL4N3UC10J

** Newmont Corp <NEM.N>:

** Barrick Mining Corp <B.N>:

** Gold Fields Ltd <GFI.N>:

** AngloGold Ashanti PLC <AU.N>:

BUZZ - Gold miners gain on softer dollar ahead of Fed minutes, Jackson Hole summit nL4N3UC0Z7

** Archer-Daniels-Midland Co <ADM.N>:

** Bunge Global SA <BG.N>:BUZZ - J.P. Morgan assumes coverage of agricultural commodities traders ADM and Bunge nL4N3UC0YL

** Hecla Mining Co HL.N>:

** Coeur Mining Inc <CDE.N>:

** Endeavour Silver Corp <EXK.N>:

** Silvercorp Metals Inc <SVM.N>:

BUZZ - Silver miners gain as white metal prices edge up on weak US dollar nL4N3UC121

** Avis Budget Group Inc <CAR.O>:BUZZ - Slides as BofA double downgrades on valuation nL6N3UC0KT

** Exxon Mobil Corp <XOM.N>:

** Chevron Corp <CVX.N>:

** APA Corp <APA.O>:

** ConocoPhillips <COP.N>:

BUZZ - Oil firms rise tracking crude as investors await next steps in Ukraine peace push nL4N3UC12D

BUZZ - UBS raises PT on oil & gas companies on stronger FCF forecasts, cost cuts nL4N3UC146

** Dycom Industries Inc <DY.N>:BUZZ - Shares slide 12% after Q2 revenue miss nL4N3UC13D

(Compiled by Rajarshi Roy and Harshita Mary Varghese)

((Rajarshi.Roy@thomsonreuters.com))