Invivyd, Inc. (Nasdaq: IVVD) has announced that the SPEAR Study Group has put forward a consensus recommendation for a clinical study design aimed at evaluating the effects of monoclonal antibody therapy on Long COVID. This proposed study, which centers on the use of anti-SARS-CoV-2 spike protein monoclonal antibodies, including Invivyd's VYD2311, will be presented at the Second Annual RECOVER-TLC Workshop, scheduled for September 9-10, 2025, in Bethesda, Maryland. The SPEAR Study Group's proposal reflects current evidence on the potential of monoclonal antibodies in treating Long COVID and identifies VYD2311 as a promising candidate. The study design is set to maintain high antiviral antibody titers over an extended period to suppress chronic infection potentially driving Long COVID. Drs. Amy Proal and David Putrino will present the study design for consideration by RECOVER-TLC, with Dr. Putrino scheduled to present the clinical study design on September 10, 2025, at 9:25 a.m. ET, followed by Dr. Proal's discussion on the antiviral landscape at 1:00 p.m. ET on the same day.