China Medical System Holdings Ltd. has announced the signing of collaboration agreements for two Class 1 innovative biologic products: the Recombinant Humanized Anti-tetanus Toxin Monoclonal Antibody Vecantoxatug Injection and the Recombinant Fully Human Bispecific Antibody Against Rabies Virus Silevimig Injection. These agreements are expected to leverage synergies with the Group's existing portfolio, potentially enhancing overall business performance. The directors of the company have stated that the terms of the agreements are fair, reasonable, and align with the interests of the company and its shareholders. Genrix Bio, the collaborating entity, is confirmed as an independent third party, and the transaction does not qualify as a connected or notifiable transaction under the Listing Rules of the Stock Exchange of Hong Kong Limited.