**AnaptysBio Announces Plans to Split into Two Public Companies** SAN DIEGO, Sept. 29, 2025 - AnaptysBio, Inc. (Nasdaq: ANAB), a clinical-stage biotechnology company specializing in immunology therapeutics, announced today that its Board of Directors has approved plans to separate its business into two independent, publicly traded companies by the end of 2026. The move is designed to unlock value by creating "Royalty Management Co," which will manage royalty and milestone payments from collaborations such as Jemperli with GSK and imsidolimab with Vanda, and "Biopharma Co," which will focus on the development and commercialization of innovative therapeutics for autoimmune and inflammatory diseases, including rosnilimab, ANB033, and ANB101. The company will discuss details of the planned separation during a conference call and webcast with investors today at 4:30pm ET.