Precision BioSciences Inc. has announced the publication of new scientific research in the journal Nucleic Acids Research, highlighting the advanced gene editing capabilities of its proprietary ARCUS platform. The peer-reviewed study demonstrates that ARCUS nucleases can achieve high-efficiency gene insertion in both dividing and non-dividing cells, with insertion frequencies reaching 60-90% in dividing cells and 20-40% in non-dividing cells. The research specifically details how the unique 3' overhangs created by ARCUS nucleases facilitate homology-mediated gene insertion, enabling a wide range of precise genome edits-including single base changes, targeted deletions, and the replacement of large DNA segments. These findings, which have already been published, underscore ARCUS's versatility and potential advantages over other genome editing technologies for treating a variety of genetic and infectious diseases.