Allogene Therapeutics Inc. disclosed that Factor Bioscience Inc. has filed a complaint in the United States District Court for the District of Delaware against Cellectis S.A. and its affiliate, alleging infringement of three U.S. patents related to gene-editing techniques. The complaint claims that Cellectis's TALEN-based gene-editing technology, which Allogene licenses for use in developing its allogeneic CAR T cell product candidates, infringes Factor's patented mRNA TALEN technology. AstraZeneca and certain affiliates are also named as defendants in the lawsuit for direct infringement. While Allogene is not currently a party to the litigation, it relies on the disputed technology for key products and could face future claims as a commercial user. Cellectis has informed Allogene of its intent to vigorously defend against Factor's allegations. The situation poses intellectual property risks for Allogene, as outlined in its recent SEC filings.