NanoViricides Inc. has announced that its clinical lead drug, NV-387, has demonstrated strong activity against the measles virus in a humanized animal model. According to the company, NV-387 can now be made available for emergency use in measles patients in response to ongoing outbreaks. The drug has completed Phase I clinical trials in healthy subjects with no reported adverse events. In preclinical studies, NV-387 treatment increased survival in animals infected with measles compared to untreated controls and showed no signs of toxicity. The company is supporting physician-initiated applications for emergency use of NV-387 and is currently focused on advancing the drug into Phase II human clinical trials. Results from the animal studies and Phase I trial have already been presented by the company.