Adlai Nortye Unveils Promising Preclinical Results for AN4035 CEACAM5-Targeting ADC at AACR Conference

Reuters

2025/10/22

Adlai Nortye Unveils Promising Preclinical Results for AN4035 CEACAM5-Targeting ADC at AACR Conference

Adlai Nortye Ltd. announced that it will deliver an oral presentation on preclinical results of its novel antibody drug conjugate $(ADC)$, AN4035, at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, scheduled for October 22-26, 2025, in Boston, MA. The presentation will highlight data showing that AN4035 demonstrated strong intracellular payload retention and potent cytotoxicity in CEACAM5-positive/RAS-addicted cancer cell lines, as well as a bystander-killing effect. The oral presentation is set for October 25, 2025, from 11:45 AM to 12:15 PM ET, with additional details to be presented in a poster session later the same day. Results from the study will be presented at the conference.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Adlai Nortye Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9549079-en) on October 22, 2025, and is solely responsible for the information contained therein.

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The presentation will highlight data showing that AN4035 demonstrated strong intracellular payload retention and potent cytotoxicity in CEACAM5-positive/RAS-addicted cancer cell lines, as well as a bystander-killing effect. The oral presentation is set for October 25, 2025, from 11:45 AM to 12:15 PM ET, with additional details to be presented in a poster session later the same day. Results from the study will be presented at the conference.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Adlai Nortye Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9549079-en) on October 22, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"LU2095319765.USD","symbol_name":"Natixis Thematics Subscription Economy R/A USD","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251022:nNDL7lRrmR:1","article_id":"2577336912","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2577336912","pubTimestamp":1761105614,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Adlai Nortye Ltd. announced that it will deliver an oral presentation on preclinical results of its novel antibody drug conjugate , AN4035, at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, scheduled for October 22-26, 2025, in Boston, MA. The presentation will highlight data showing that AN4035 demonstrated strong intracellular payload retention and potent cytotoxicity in CEACAM5-positive/RAS-addicted cancer cell lines, as well as a bystander-killing effect. The oral presentation is set for October 25, 2025, from 11:45 AM to 12:15 PM ET, with additional details to be presented in a poster session later the same day. Results from the study will be presented at the conference.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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The presentation will highlight data showing that AN4035 demonstrated strong intracellular payload retention and potent cytotoxicity in CEACAM5-positive/RAS-addicted cancer cell lines, as well as a bystander-killing effect. The oral presentation is set for October 25, 2025, from 11:45 AM to 12:15 PM ET, with additional details to be presented in a poster session later the same day. Results from the study will be presented at the conference.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Adlai Nortye Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. 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