Heartflow Inc. has announced new developments in clinical research and product offerings related to coronary intervention planning. The company's PLAN CALCIUM study evaluated the impact of integrating Heartflow Plaque Analysis with coronary CTA imaging and FFRCT analysis to inform interventional cardiologists' decisions on percutaneous coronary intervention $(PCI)$ in patients with highly calcified lesions. Data from the PLAN CALCIUM study will be presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2025 conference, scheduled for October 26, 2025. Additionally, Heartflow will initiate the NAVIGATE-PCI Registry in 2026, enrolling approximately 2,500 patients across 30 U.S. sites. This registry will assess the effect of the company's PCI Navigator tool on physician confidence, procedural safety, efficiency, strategy, and patient outcomes compared to standard care. Heartflow will also demonstrate PCI Navigator at their exhibit booth during the TCT 2025 conference.