Repare Therapeutics Inc. announced that an abstract detailing preliminary data from its Phase 1 LIONS trial of RP-1664, a first-in-class PLK4 inhibitor, has been made available. The data pertain to the use of RP-1664 as monotherapy in patients with advanced solid tumors, both with and without TRIM37 amplification. The preliminary results will be presented at the 37th AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston, Massachusetts.
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