Enliven Therapeutics Reports Promising ELVN-001 Results in CML Patients With Atypical Fusion Transcripts
Enliven Therapeutics Inc. announced that it will present preliminary clinical data from the ongoing ENABLE Phase 1a/1b trial of ELVN-001, a selective active site inhibitor of BCR::ABL1, in chronic myeloid leukemia (CML) patients with atypical fusion transcripts at the 67th Annual American Society of Hematology $(ASH)$ 2025 Annual Meeting. The presentation is scheduled for December 7, 2025, in Orlando, Florida. According to the company, ELVN-001 demonstrated encouraging anti-CML activity in a heavily pretreated patient population, including those with the e13a3 fusion transcript, which is resistant to certain tyrosine kinase inhibitors. Detailed data will be available following the presentation on Enliven Therapeutics' website.
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