Nuvation Bio Inc. has provided an update highlighting recent developments across its oncology portfolio. The company reported that IBTROZI™ (taletrectinib), a next-generation ROS1 inhibitor, received approval in the U.S., Japan, and China for advanced ROS1-positive non-small cell lung cancer (NSCLC), with 204 new patient starts in Q3 2025. Safusidenib, a brain-penetrant mIDH1 inhibitor, is entering a pivotal study for high-grade IDH1-mutant glioma, with plans to potentially include high-risk, low-grade patients. NUV-1511, a clinical-stage drug-drug conjugate, is in Phase 1/2 evaluation, while NUV-868, a BD2-selective BET inhibitor, has completed Phase 1 and Phase 1b studies. The company reported a cash balance of $549 million as of September 30, 2025, with additional funding available under a term loan agreement. You can access the full presentation through the link below.