Pacira BioSciences Completes Enrollment in Phase 2 Trial for PCRX-201 Osteoarthritis Gene Therapy

Reuters

2025/11/05

Pacira BioSciences Completes Enrollment in Phase 2 Trial for PCRX-201 Osteoarthritis Gene Therapy

Pacira BioSciences Inc. has announced the completion of patient enrollment in Part A of its Phase 2 ASCEND study evaluating PCRX-201 (enekinragene inzadenovec) for the treatment of osteoarthritis of the knee. The ASCEND study is a two-part, multicenter trial assessing the safety and efficacy of PCRX-201, a locally administered gene therapy designed to increase anti-inflammatory IL-1Ra production in the knee joint. Part A of the study involved approximately 45 patients who were randomized to receive one of two doses of PCRX-201 or saline, with all cohorts receiving pretreatment with an intra-articular corticosteroid. The results from Part A, which will inform dose selection and manufacturing for Part B, are expected to be reported near the end of 2026. No results have been presented yet.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Pacira Biosciences Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9568980-en) on November 05, 2025, and is solely responsible for the information contained therein.

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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Pacira Biosciences Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9568980-en) on November 05, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"IE00B3QW5Z07.USD","symbol_name":"GUINNESS GLOBAL MONEY MANAGERS \"C\" (USD) ACC","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251105:nNDL7fWq7h:1","article_id":"2581234727","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2581234727","pubTimestamp":1762347640,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Pacira BioSciences Inc. has announced the completion of patient enrollment in Part A of its Phase 2 ASCEND study evaluating PCRX-201  for the treatment of osteoarthritis of the knee. 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The ASCEND study is a two-part, multicenter trial assessing the safety and efficacy of PCRX-201, a locally administered gene therapy designed to increase anti-inflammatory IL-1Ra production in the knee joint. Part A of the study involved approximately 45 patients who were randomized to receive one of two doses of PCRX-201 or saline, with all cohorts receiving pretreatment with an intra-articular corticosteroid. The results from Part A, which will inform dose selection and manufacturing for Part B, are expected to be reported near the end of 2026. No results have been presented yet.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 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