Prothena Highlights Positive Phase 2 Results for Coramitug in ATTR Amyloidosis

Reuters
11/11
Prothena Highlights Positive Phase 2 Results for Coramitug in ATTR Amyloidosis

Prothena Corporation plc announced the publication of Phase 2 clinical trial data for coramitug (formerly PRX004), a humanized monoclonal antibody being developed for the treatment of transthyretin amyloid cardiomyopathy (ATTR-CM). The results were presented during a late-breaking session at the American Heart Association Scientific Sessions on November 10, 2025, and published in the journal Circulation. Coramitug is being developed by Novo Nordisk as part of its acquisition of Prothena's ATTR amyloidosis business and pipeline. Novo Nordisk has recently initiated the Phase 3 CLEOPATTRA clinical trial to evaluate the effects of coramitug versus placebo on cardiovascular outcomes in participants with ATTR-CM.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Prothena Corporation plc published the original content used to generate this news brief via Business Wire (Ref. ID: 20251111691007) on November 11, 2025, and is solely responsible for the information contained therein.

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