Simcere Launches Phase II Trial of SIM0278 for Moderate-to-Severe Atopic Dermatitis

Reuters

11/10

Simcere Launches Phase II Trial of SIM0278 for Moderate-to-Severe Atopic Dermatitis

Simcere Pharmaceutical Group Ltd. announced that its IL-2 mutant fusion protein, SIM0278, has entered a Phase II clinical trial in China for the treatment of moderate-to-severe atopic dermatitis. The first dose in the study was administered at Hangzhou First People's Hospital. This randomized, double-blind, placebo-controlled, multi-center Phase II study aims to evaluate the efficacy, safety, and pharmacokinetics of continuous subcutaneous administration of SIM0278 in participants with moderate-to-severe atopic dermatitis. Results from this Phase II study have not yet been presented. Preliminary safety and efficacy data from a completed Phase I clinical study in China have previously demonstrated good tolerability and appropriate pharmacokinetic properties for SIM0278.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Simcere Pharmaceutical Group Ltd. published the original content used to generate this news brief via PR Newswire (Ref. ID: EN19985) on November 10, 2025, and is solely responsible for the information contained therein.

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The first dose in the study was administered at Hangzhou First People's Hospital. This randomized, double-blind, placebo-controlled, multi-center Phase II study aims to evaluate the efficacy, safety, and pharmacokinetics of continuous subcutaneous administration of SIM0278 in participants with moderate-to-severe atopic dermatitis. Results from this Phase II study have not yet been presented. Preliminary safety and efficacy data from a completed Phase I clinical study in China have previously demonstrated good tolerability and appropriate pharmacokinetic properties for SIM0278.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Simcere Pharmaceutical Group Ltd. published the original content used to generate this news brief via PR Newswire (Ref. ID: EN19985) on November 10, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK1583","symbol_name":"高瓴概念","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nNDLc8Dsjb:1","article_id":"2582821400","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2582821400","pubTimestamp":1762768089,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Simcere Pharmaceutical Group Ltd. announced that its IL-2 mutant fusion protein, SIM0278, has entered a Phase II clinical trial in China for the treatment of moderate-to-severe atopic dermatitis. The first dose in the study was administered at Hangzhou First People's Hospital. This randomized, double-blind, placebo-controlled, multi-center Phase II study aims to evaluate the efficacy, safety, and pharmacokinetics of continuous subcutaneous administration of SIM0278 in participants with moderate-to-severe atopic dermatitis. Results from this Phase II study have not yet been presented. Preliminary safety and efficacy data from a completed Phase I clinical study in China have previously demonstrated good tolerability and appropriate pharmacokinetic properties for SIM0278.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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This randomized, double-blind, placebo-controlled, multi-center Phase II study aims to evaluate the efficacy, safety, and pharmacokinetics of continuous subcutaneous administration of SIM0278 in participants with moderate-to-severe atopic dermatitis. Results from this Phase II study have not yet been presented. Preliminary safety and efficacy data from a completed Phase I clinical study in China have previously demonstrated good tolerability and appropriate pharmacokinetic properties for SIM0278.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Simcere Pharmaceutical Group Ltd. published the original content used to generate this news brief via PR Newswire (Ref. 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