Editas Medicine Inc. reported its third quarter 2025 financial results and provided business updates. The company highlighted preclinical proof-of-concept data presented at the American Heart Association (AHA) and the European Society of Gene and Cell Therapy (ESGCT), demonstrating that its lead candidate, EDIT-401, achieved over 90% reduction in LDL cholesterol levels in non-human primates. In mouse models, the LDL-C reduction was maintained over a three-month study, supporting the durability of the effect. Editas Medicine remains on track to submit an investigational new drug (IND) or clinical trial application $(CTA)$ for EDIT-401 by mid-2026, with initial human proof-of-concept data anticipated by year-end 2026. The company has extended its cash runway into the third quarter of 2027 through proceeds from sales of its common stock under its at-the-market facility and continued financial discipline. Editas also announced participation in the 8th Annual Evercore Healthcare Conference on December 2, 2025.