CalciMedica Reports Auxora Improves Kidney Function in Preclinical AKI Study

Reuters

2025/11/10

CalciMedica Reports Auxora Improves Kidney Function in Preclinical AKI Study

CalciMedica Inc., a clinical-stage biopharmaceutical company, announced the presentation of new preclinical data on its calcium release-activated calcium (CRAC) channel inhibitor, Auxora, at the American Society of Nephrology (ASN) Kidney Week 2025. The results, already presented, demonstrated that treatment with Auxora significantly reduced IL-17-related inflammation in both the kidney and lung, increased glomerular filtration rate $(GFR)$, and decreased renal injury in a rat model of acute kidney injury (AKI). These findings support the ongoing clinical evaluation of Auxora in the Phase 2 KOURAGE trial for patients with severe AKI and acute hypoxemic respiratory failure (AHRF). The full presentation is available on CalciMedica's investor relations website.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. CalciMedica Inc. published the original content used to generate this news brief via PR Newswire (Ref. ID: LA18204) on November 10, 2025, and is solely responsible for the information contained therein.

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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. CalciMedica Inc. published the original content used to generate this news brief via PR Newswire (Ref. ID: LA18204) on November 10, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4007","symbol_name":"制药","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nNDLbXHjyD:1","article_id":"2582873923","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2582873923","pubTimestamp":1762776217,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"CalciMedica Inc., a clinical-stage biopharmaceutical company, announced the presentation of new preclinical data on its calcium release-activated calcium  channel inhibitor, Auxora, at the American Society of Nephrology  Kidney Week 2025. 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