Monopar Therapeutics Inc. announced new data and analyses from the Phase 2 ALXN1840-WD-204 copper balance study evaluating tiomolybdate choline in patients with Wilson disease. The results, which were presented at the American Association for the Study of Liver Diseases (AASLD) - The Liver Meeting® 2025, demonstrated that treatment with ALXN1840 led to a rapid and sustained improvement in daily copper balance, primarily through increased fecal copper excretion. The mean daily copper balance among patients treated with ALXN1840 was significantly lower compared to their pre-treatment baseline. Additional nonclinical and clinical data supporting these findings from the ALXN1840-WD-204 study were also presented at the meeting.
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