Hansoh Pharma Reports Positive Phase 2 Results for HS-20089 in Platinum-Resistant Ovarian Cancer

Reuters

11/10

Hansoh Pharma Reports Positive Phase 2 Results for HS-20089 in Platinum-Resistant Ovarian Cancer

Hansoh Pharmaceutical Group Co., Ltd. has announced positive Phase 2 clinical trial results for HS-20089 (also known as GSK5733584), a B7-H4-targeted antibody-drug conjugate $(ADC)$, in patients with platinum-resistant ovarian cancer $(PROC)$. The findings were presented as an oral presentation at the 2025 International Gynecologic Cancer Society (IGCS) Annual Global Meeting and were previously shared at the 2025 European Society for Medical Oncology (ESMO) Annual Meeting. As of the June 20, 2025 data cutoff, HS-20089 demonstrated a confirmed objective response rate $(ORR)$ of 48.5% and a duration of response (DoR) of 6.8 months in heavily pretreated PROC patients, regardless of tumor B7-H4 expression. The median progression-free survival (mPFS) was 6.4 months and the median overall survival (mOS) was 14.6 months, with a median follow-up time of 11.5 months. The safety profile was consistent with previous studies, and no cases of interstitial lung disease were reported. A Phase 3 study is ongoing.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Hansoh Pharmaceutical Group Co. Ltd. published the original content used to generate this news brief on November 10, 2025, and is solely responsible for the information contained therein.

免责声明：投资有风险，本文并非投资建议，以上内容不应被视为任何金融产品的购买或出售要约、建议或邀请，作者或其他用户的任何相关讨论、评论或帖子也不应被视为此类内容。本文仅供一般参考，不考虑您的个人投资目标、财务状况或需求。TTM对信息的准确性和完整性不承担任何责任或保证，投资者应自行研究并在投资前寻求专业建议。

热议股票

1
2
3
4
5
6
7
8
9
10

{"basename":"/hans","ssrTDKData":{"titleTemplate":"%s - 老虎证券","title":"老虎证券全球投资理财平台| 一站式投资美股新股港股A股","description":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","keywords":"老虎证券,老虎证券开户,老虎券商,老虎证券官网,老虎证券app,tigertrade老虎证券,股票,炒股,新加坡股票交易平台,投资,投资理财","social":{"ogDescription":"老虎证券助您一站式投资美股，新股，港股，A股等全球金融理财产品。新加坡华人最信赖的在线投资平台，现在加入即享低费用，24/5 无时差炒美股投资理财！","ogImage":"https://c1.itigergrowtha.com/portal5/static/media/og-logo.be62fbe1.png","ogUrl":"https://www.itiger.com/hans/news/2582981074"},"companyName":"老虎证券"},"pageData":{"isMobile":false,"isTiger":false,"isTTM":true,"region":"SGP","license":"TBSG","edition":"fundamental"},"isCrawlerRequest":true,"__swrFallback__":{"@#url:\"https://stock-news.skytigris.cn/v3/news\",params:#id:\"2582981074\",edition:\"fundamental\",auth_exemption:1,,,undefined,":{"share":"https://ttm.financial/m/news/2582981074?lang=zh_CN&edition=fundamental","thumbnail":"","is_english":true,"pubTime":"2025-11-10 10:36","share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","id":"2582981074","market":"nz","top_or_hot":-1,"title":"Hansoh Pharma Reports Positive Phase 2 Results for HS-20089 in Platinum-Resistant Ovarian Cancer","media":"Reuters","content":"<html xmlns=\"http://www.w3.org/1999/xhtml\" xmlns:newsg2=\"http://iptc.org/std/nar/2006-10-01/\" xmlns:xhtml=\"http://www.w3.org/1999/xhtml\"><head><title>\n      Hansoh Pharma Reports Positive Phase 2 Results for HS-20089 in Platinum-Resistant Ovarian Cancer\n    </title></head><body><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n        Hansoh Pharmaceutical Group Co., Ltd. has announced positive Phase 2 clinical trial results for HS-20089 (also known as GSK5733584), a B7-H4-targeted antibody-drug conjugate <a href=\"https://laohu8.com/S/ADC\">$(ADC)$</a>, in patients with platinum-resistant ovarian cancer <a href=\"https://laohu8.com/S/PROC\">$(PROC)$</a>. The findings were presented as an oral presentation at the 2025 International Gynecologic Cancer Society (IGCS) Annual Global Meeting and were previously shared at the 2025 European Society for Medical Oncology (ESMO) Annual Meeting. As of the June 20, 2025 data cutoff, HS-20089 demonstrated a confirmed objective response rate <a href=\"https://laohu8.com/S/ORR\">$(ORR)$</a> of 48.5% and a duration of response (DoR) of 6.8 months in heavily pretreated PROC patients, regardless of tumor B7-H4 expression. The median progression-free survival (mPFS) was 6.4 months and the median overall survival (mOS) was 14.6 months, with a median follow-up time of 11.5 months. The safety profile was consistent with previous studies, and no cases of interstitial lung disease were reported. A Phase 3 study is ongoing.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Hansoh Pharmaceutical Group Co. Ltd. published the original content used to generate this news brief on November 10, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>","source":null,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Hansoh Pharma Reports Positive Phase 2 Results for HS-20089 in Platinum-Resistant Ovarian Cancer</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nHansoh Pharma Reports Positive Phase 2 Results for HS-20089 in Platinum-Resistant Ovarian Cancer\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1032215980\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Reuters </p>\n<p class=\"h-time\">2025-11-10 10:36</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<html xmlns=\"http://www.w3.org/1999/xhtml\" xmlns:newsg2=\"http://iptc.org/std/nar/2006-10-01/\" xmlns:xhtml=\"http://www.w3.org/1999/xhtml\"><head><title>\n      Hansoh Pharma Reports Positive Phase 2 Results for HS-20089 in Platinum-Resistant Ovarian Cancer\n    </title></head><body><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n        Hansoh Pharmaceutical Group Co., Ltd. has announced positive Phase 2 clinical trial results for HS-20089 (also known as GSK5733584), a B7-H4-targeted antibody-drug conjugate <a href=\"https://laohu8.com/S/ADC\">$(ADC)$</a>, in patients with platinum-resistant ovarian cancer <a href=\"https://laohu8.com/S/PROC\">$(PROC)$</a>. The findings were presented as an oral presentation at the 2025 International Gynecologic Cancer Society (IGCS) Annual Global Meeting and were previously shared at the 2025 European Society for Medical Oncology (ESMO) Annual Meeting. As of the June 20, 2025 data cutoff, HS-20089 demonstrated a confirmed objective response rate <a href=\"https://laohu8.com/S/ORR\">$(ORR)$</a> of 48.5% and a duration of response (DoR) of 6.8 months in heavily pretreated PROC patients, regardless of tumor B7-H4 expression. The median progression-free survival (mPFS) was 6.4 months and the median overall survival (mOS) was 14.6 months, with a median follow-up time of 11.5 months. The safety profile was consistent with previous studies, and no cases of interstitial lung disease were reported. A Phase 3 study is ongoing.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Hansoh Pharmaceutical Group Co. Ltd. published the original content used to generate this news brief on November 10, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"03692","symbol_name":"翰森制药","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nNDL9HFFTJ:1","article_id":"2582981074","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2582981074","pubTimestamp":1762742211,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Hansoh Pharmaceutical Group Co., Ltd. has announced positive Phase 2 clinical trial results for HS-20089 , a B7-H4-targeted antibody-drug conjugate , in patients with platinum-resistant ovarian cancer . The findings were presented as an oral presentation at the 2025 International Gynecologic Cancer Society  Annual Global Meeting and were previously shared at the 2025 European Society for Medical Oncology  Annual Meeting. As of the June 20, 2025 data cutoff, HS-20089 demonstrated a confirmed objective response rate  of 48.5% and a duration of response  of 6.8 months in heavily pretreated PROC patients, regardless of tumor B7-H4 expression. The median progression-free survival  was 6.4 months and the median overall survival  was 14.6 months, with a median follow-up time of 11.5 months. The safety profile was consistent with previous studies, and no cases of interstitial lung disease were reported. A Phase 3 study is ongoing.","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"03692":"翰森制药","BK1191":"制药","BK1583":"高瓴概念","BK1589":"北水核心资产"},"translate_title":"豪森制药报告HS-20089治疗铂类耐药卵巢癌的2期积极结果","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"03692":0.9},"content_text":"Hansoh Pharma Reports Positive Phase 2 Results for HS-20089 in Platinum-Resistant Ovarian Cancer\n    \n\n        Hansoh Pharmaceutical Group Co., Ltd. has announced positive Phase 2 clinical trial results for HS-20089 (also known as GSK5733584), a B7-H4-targeted antibody-drug conjugate $(ADC)$, in patients with platinum-resistant ovarian cancer $(PROC)$. The findings were presented as an oral presentation at the 2025 International Gynecologic Cancer Society (IGCS) Annual Global Meeting and were previously shared at the 2025 European Society for Medical Oncology (ESMO) Annual Meeting. As of the June 20, 2025 data cutoff, HS-20089 demonstrated a confirmed objective response rate $(ORR)$ of 48.5% and a duration of response (DoR) of 6.8 months in heavily pretreated PROC patients, regardless of tumor B7-H4 expression. The median progression-free survival (mPFS) was 6.4 months and the median overall survival (mOS) was 14.6 months, with a median follow-up time of 11.5 months. The safety profile was consistent with previous studies, and no cases of interstitial lung disease were reported. A Phase 3 study is ongoing.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Hansoh Pharmaceutical Group Co. Ltd. published the original content used to generate this news brief on November 10, 2025, and is solely responsible for the information contained therein.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"1","news_tag":"dataReport,express","news_rank":0,"symbols":[],"gpt_button":0,"need_auth":false,"code":"91000000","status":"200"}}}