European equities traded in the US as American depositary receipts were rising on Wednesday morning, up 0.5% to 1,640.07 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by biopharmaceutical company DBV Technologies (DBVT) and pharmaceutical giant Novo Nordisk (NVO), which climbed 5% and 2%, respectively.

They were followed by bank Santander (SAN), which rose 2.3%.

The decliners from continental Europe were led by cybersecurity company Wisekey (WKEY) and solar energy firm Turbo Energy (TURB), which fell 4.9% and 3.2%, respectively.

They were followed by energy company Equinor (EQNR), which was down 2.1%.

From the UK and Ireland, the gainers were led by clinical-stage pharmaceutical company Centessa Pharmaceuticals (CNTA) and Argo Blockchain (ARBK), which gained 12% and 5.6%, respectively.

The decliners from the UK and Ireland were led by early commercial-stage biopharmaceutical company Autolus Therapeutics (AUTL), which dropped nearly 10%.