Estrella Immunopharma Inc. announced that its STARLIGHT-1 clinical trial has advanced to Phase II following a positive recommendation from an independent Data Safety Monitoring Board (DSMB). The decision was based on safety data from the Phase I dose escalation phase, during which no treatment-related serious adverse events were reported among nine patients, and all evaluable patients in the high-dose cohort achieved a complete response at Month 1. The STARLIGHT-1 trial is evaluating EB103, a CD19-redirected ARTEMIS® T-cell therapy, in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma. The expansion phase will further assess safety and preliminary efficacy, with results to be collected and used to inform future pivotal trial strategies. Results from the expansion phase have not yet been presented.