CytoDyn Inc., a clinical-stage oncology company, announced updated results from a retrospective follow-up analysis involving 28 women with metastatic triple-negative breast cancer (mTNBC) who participated in three leronlimab clinical trials. The findings, which will be presented as a poster at the San Antonio Breast Cancer Symposium on December 12, 2025, indicate that leronlimab treatment is associated with upregulation of PD-L1 in circulating tumor cells and cancer-associated macrophage-like cells. Among patients who demonstrated significant PD-L1 induction and subsequently received immune checkpoint inhibitors, all remain alive after a median of 60.9 months, with three showing no evidence of disease. No dose-limiting toxicities were observed, and no patients withdrew due to treatment-related adverse events. A copy of the presentation will be made available on CytoDyn's website after the symposium.