Personalis NeXT Personal Test Shows High Sensitivity for Lung Cancer MRD Detection in Landmark Study

Reuters
2025/12/11
<a href="https://laohu8.com/S/PSNL">Personalis</a> NeXT Personal Test Shows High Sensitivity for Lung Cancer MRD Detection in Landmark Study

Personalis, Inc. announced the publication of results from a major clinical study utilizing its NeXT Personal® test for ultrasensitive detection of molecular residual disease (MRD) in non-small cell lung cancer (NSCLC). The study, published in the journal Cell, analyzed 431 NSCLC patients over a median of more than five years and demonstrated that the NeXT Personal test provides highly sensitive and specific detection of circulating tumor DNA (ctDNA) from diagnosis through long-term surveillance. Key findings include the ability to detect residual and recurrent cancer at multiple stages of patient care, with approximately 36-43% of detections in the ultrasensitive range. Additionally, the study found that patients who did not clear ctDNA during adjuvant chemotherapy were more than five times as likely to experience relapse compared to those who cleared ctDNA. The results have already been published and presented in Cell.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Personalis Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20251211863347) on December 11, 2025, and is solely responsible for the information contained therein.

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