Insmed Scraps Development of Sinus Drug After Mid-Stage Study Failure

Reuters
2025/12/18

Dec 17 (Reuters) - Insmed said on Wednesday it had discontinued the development of its experimental anti-inflammatory drug to treat a chronic sinus condition after it failed to show benefit in a mid-stage study, sending its shares down nearly 19% in extended trading.

The drug, brensocatib, failed to meet the main goal of improving sinus-related symptoms such as nasal congestion in patients with chronic rhinosinusitis without nasal polyps, an inflammatory condition of the sinuses.

Brensocatib, branded as Brinsupri, is approved in the U.S. to treat non-cystic fibrosis bronchiectasis, a chronic lung condition characterized by permanently damaged airways.

The mid-stage study tested two doses of brensocatib against a placebo in 288 patients for 24 weeks in addition to a nasal spray treatment to relieve symptoms.

The drug was generally safe, with no new safety signals, the company said, adding that it plans to present these data at a future meeting.

Insmed also announced it had acquired a new experimental antibody, INS1148, which it plans to develop for lung and immune diseases such as interstitial lung disease and moderate-to-severe asthma.

应版权方要求,你需要登录查看该内容

免责声明:投资有风险,本文并非投资建议,以上内容不应被视为任何金融产品的购买或出售要约、建议或邀请,作者或其他用户的任何相关讨论、评论或帖子也不应被视为此类内容。本文仅供一般参考,不考虑您的个人投资目标、财务状况或需求。TTM对信息的准确性和完整性不承担任何责任或保证,投资者应自行研究并在投资前寻求专业建议。

热议股票

  1. 1
     
     
     
     
  2. 2
     
     
     
     
  3. 3
     
     
     
     
  4. 4
     
     
     
     
  5. 5
     
     
     
     
  6. 6
     
     
     
     
  7. 7
     
     
     
     
  8. 8
     
     
     
     
  9. 9
     
     
     
     
  10. 10