Sol-Gel to End SGT-210 Trial in Darier Disease

MT Newswires Live

2025/12/18

Sol-Gel Technologies (SLGL) said Wednesday data from its phase 1b trial of SGT-210 in Darier Disease did not show differentiation between SGT-210 and vehicle on efficacy following unblinding.

"The study did not demonstrate a signal of superiority of active treatment versus vehicle," said Executive Chairman Mori Arkin. "We have therefore decided not to advance to the next stage of development in this indication."

Arkin said the firm plans to pursue "very" small, low-cost feasibility studies in other areas where the mechanistic rationale for SGT-210 is strong.

Shares of Sol-Gel were over 2% lower in recent trading.

Price: 41.25, Change: -0.88, Percent Change: -2.08

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