4D Molecular Therapeutics Reports Positive Interim Phase 1 Results for 4D-710 in Cystic Fibrosis

Reuters

2025/12/17

<a href="https://laohu8.com/S/FDMT">4D Molecular Therapeutics</a> Reports Positive Interim Phase 1 Results for 4D-710 in Cystic Fibrosis

4D Molecular Therapeutics Inc. announced positive interim clinical data from its Phase 1 AEROW clinical trial evaluating 4D-710 for the treatment of cystic fibrosis $(CF)$ lung disease. The results showed that the selected Phase 2 dose of 4D-710 was well tolerated, with no severe adverse events related to the drug, and achieved physiologically relevant levels of CFTR expression. Clinically meaningful activity was observed in multiple endpoints, including lung function and quality of life measures, with follow-up through one year. The data were presented in a company webcast on December 17, 2025. Enrollment for the Phase 2 Dose-Expansion cohort is expected to be completed in the first half of 2026, with a program update anticipated in the second half of 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 4D Molecular Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9603443-en) on December 17, 2025, and is solely responsible for the information contained therein.

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The results showed that the selected Phase 2 dose of 4D-710 was well tolerated, with no severe adverse events related to the drug, and achieved physiologically relevant levels of CFTR expression. Clinically meaningful activity was observed in multiple endpoints, including lung function and quality of life measures, with follow-up through one year. The data were presented in a company webcast on December 17, 2025. Enrollment for the Phase 2 Dose-Expansion cohort is expected to be completed in the first half of 2026, with a program update anticipated in the second half of 2026.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. 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The results showed that the selected Phase 2 dose of 4D-710 was well tolerated, with no severe adverse events related to the drug, and achieved physiologically relevant levels of CFTR expression. Clinically meaningful activity was observed in multiple endpoints, including lung function and quality of life measures, with follow-up through one year. The data were presented in a company webcast on December 17, 2025. Enrollment for the Phase 2 Dose-Expansion cohort is expected to be completed in the first half of 2026, with a program update anticipated in the second half of 2026.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. 4D Molecular Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9603443-en) on December 17, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"IE00BGHQF748.EUR","symbol_name":"GUINNESS GLOBAL MONEY MANAGERS \"C\" (EUR) ACC","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251217:nNDL9rvlDM:1","article_id":"2592999283","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2592999283","pubTimestamp":1765972829,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"4D Molecular Therapeutics Inc. announced positive interim clinical data from its Phase 1 AEROW clinical trial evaluating 4D-710 for the treatment of cystic fibrosis  lung disease. 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The results showed that the selected Phase 2 dose of 4D-710 was well tolerated, with no severe adverse events related to the drug, and achieved physiologically relevant levels of CFTR expression. Clinically meaningful activity was observed in multiple endpoints, including lung function and quality of life measures, with follow-up through one year. The data were presented in a company webcast on December 17, 2025. Enrollment for the Phase 2 Dose-Expansion cohort is expected to be completed in the first half of 2026, with a program update anticipated in the second half of 2026.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. 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