This article was automatically generated using Dow Jones technology.

Shares of small-cap companies added Wednesday, as the Russell 2000 Index added 0.3%, and the S&P Small Cap 600 Index was up 0.4%.

Among companies with a market value of $1 billion to $6.7 billion, Dynavax Technologies Corp. was the best performer during the session, surging 38%, followed by Edgewise Therapeutics Inc., which surged 26%. Agios Pharmaceuticals Inc. shares jumped 19%, Travere Therapeutics Inc. jumped 14%, and shares of Kodiak Sciences Inc. jumped 13%.

Hycroft Mining Holding Corp. was the biggest laggard, dropping 8.0%, followed by shares of Sable Offshore Corp. Cl A, which fell 4.8%. Shares of Nano Nuclear Energy Inc. fell 4.6%, Mind Medicine (MindMed) Inc. shares declined 4.2%, and Perpetua Resources Corp. dropped 4.0%.

Major stock indexes in the U.S. closed up Wednesday with the Nasdaq Composite Index gaining 0.2%. Meanwhile, the S&P 500 Index increased 0.3%, and the Dow Jones Industrial Average added 0.6%.

Data source: Dow Jones Market Data, FactSet

(END) Dow Jones Newswires

December 24, 2025 16:21 ET (21:21 GMT)

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