ALX Oncology Doses First Patient in Phase 2 Trial of Evorpacept for HER2-Positive Metastatic Breast Cancer

Reuters

01/08

ALX Oncology Doses First Patient in Phase 2 Trial of Evorpacept for HER2-Positive Metastatic Breast Cancer

ALX Oncology Holdings Inc. announced the initiation of the third dose cohort in its Phase 1 clinical trial of ALX2004, a novel EGFR-targeted antibody-drug conjugate, for participants with advanced or metastatic EGFR-expressing solid tumors. The Phase 1 trial includes a dose escalation portion currently enrolling patients with previously treated advanced or metastatic non-small cell lung cancer, head and neck squamous cell carcinoma, esophageal squamous cell carcinoma, and colorectal cancer. The company expects to provide an initial safety update from the ALX2004 trial in the first half of 2026. No results have been presented yet.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. ALX Oncology Holdings Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9622081-en) on January 08, 2026, and is solely responsible for the information contained therein.

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ID: GNW9622081-en) on January 08, 2026, and is solely responsible for the information contained therein.</span></i>\n</p>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"LU2095319765.USD","symbol_name":"Natixis Thematics Subscription Economy R/A USD","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260108:nNDLbnpwxc:1","article_id":"2601621903","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2601621903","pubTimestamp":1767879018,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"ALX Oncology Holdings Inc. announced the initiation of the third dose cohort in its Phase 1 clinical trial of ALX2004, a novel EGFR-targeted antibody-drug conjugate, for participants with advanced or metastatic EGFR-expressing solid tumors. 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