Wall Street's main indexes extended their rally on Tuesday, with the Dow at a record high on a boost from healthcare and technology stocks, while investors positioned for the week's key jobs report to gauge the Federal Reserve's policy outlook. .N

At 13:32 EST, the Dow Jones Industrial Average .DJI was up 0.88% at 49,410.77.The S&P 500 .SPX was up 0.47% at 6,934.68, and the Nasdaq Composite .IXIC was up 0.44% at 23,499.51.

The top three S&P 500 .PG.INX percentage gainers:

** Sandisk Corp SNDK.OQ, up 22.8%

** Western Digital Corp WDC.OQ, up 15.3%

** Seagate Technology Holdings PLC STX.OQ, up 12.7%

The top three S&P 500 .PL.INX percentage losers:

** American International Group Inc AIG.N, down 8.4%

** Johnson Controls International PLC JCI.N, down 6.3%

** Tesla Inc TSLA.OQ, down 4.9%

The top three NYSE .PG.N percentage gainers:

** Lithium Argentina AG LAR.N, up 14.9%

** Spire Global Inc SPIR.N, up 14.0%

** agilon health inc AGL.N, up 13.8%

The top three NYSE .PL.N percentage losers:

** LiveWire Group Inc LVWR.N, down 13.4%

** Natuzzi SpA NTZ.N, down 12.4%

** T1 Energy Inc TE.N, down 10.7%

The top three Nasdaq .PG.O percentage gainers:

** Alumis Inc ALMS.OQ, up 92.7%

** Autozi Internet Technology (Global) Ltd AZI.OQ, up 88.4%

** Sky Quarry Inc SKYQ.OQ, up 60.8%

The top three Nasdaq .PL.O percentage losers:

** Instil Bio Inc TIL.OQ, down 47.1%

** MOBIX LABS, INC. MOBX.OQ, down 40.3%

** Oriental Culture Holding Ltd OCG.OQ, down 36.2%

** International Flavors & Fragrances Inc IFF.N:BUZZ - MS favours 'structural winners' in ingredients, cuts DSM, lifts Givaudan nL6N3Y70FD

** Microchip Technology Inc MCHP.O:BUZZ - Jumps as third-quarter sales outlook improves nL6N3Y70CF

** Intel Corp INTC.O:BUZZ - Rises after launching Panther Lake AI chip for laptops nL4N3Y70L9

** Hecla Mining Co HL.N:

** Coeur Mining Inc CDE.N:

** Endeavour Silver Corp EXK.N:

** Silvercorp Metals Inc SVM.N:

BUZZ - Silver miners rise as prices surge on rate cut bets nL6N3Y70TC

** Vistra Corp VST.N:BUZZ - Gains after $4.7 billion deal to buy Cogentrix Energy nL6N3Y70KU

** OneStream Inc OS.O:BUZZ - Jumps after Bloomberg News reports Hg Capital eyes acquisition nL6N3Y70K6

** Aeva Technologies Inc AEVA.O:BUZZ - Soars on Nvidia sensor deal nL6N3Y70MG

** Zeta Global Holdings Corp ZETA.N:BUZZ - Jumps on OpenAI partnership nL6N3Y70LT

** Rentokil Initial PLC RTO.N:

** Ferguson Enterprises Inc FERG.N:BUZZ - MS still upbeat on European business services for 2026 nL8N3Y70BY

** Apogee Therapeutics Inc APGE.O:BUZZ - Rises as asthma drug shows promise in early trial nL4N3Y70N9

** Under Armour Inc UAA.N:BUZZ - Jumps as Fairfax Financial acquires 22% stake nL6N3Y70NI

** AngioDynamics Inc ANGO.O:BUZZ - Up after annual sales forecast raise nL6N3Y70NP

** Crinetics Pharmaceuticals Inc CRNX.O:BUZZ - Ticks down after announcing $350 mln stock offering nL6N3Y70NV

** Albemarle Corp ALB.N:BUZZ - Gains after Berenberg raises PT nL6N3Y70UA

** Jackson Financial Inc JXN.N:BUZZ - Rises after TPG invests $500 million nL6N3Y70NS

** Wells Fargo & Co WFC.N:BUZZ - JP Morgan lifts PT of Wells Fargo on net interest income growth optimism nL4N3Y70P3

** Alumis Inc ALMS.O:BUZZ - Jumps after skin disease drug meets main goal in late-stage trials nL4N3Y70QN

** Realty Income Corp O.N:BUZZ - Dips after $750 mln convertible bond sale nL6N3Y70PA

** Alkermes PLC ALKS.O:BUZZ - Rises as narcolepsy drug gets FDA breakthrough tag nL4N3Y70QW

** Ball Corp BALL.N:BUZZ - Rises after Citigroup upgrades to 'buy' nL6N3Y70ON

** Globe Life Inc GL.N:BUZZ - Falls after Evercore ISI downgrades rating nL6N3Y70OQ

** Aclaris Therapeutics Inc ACRS.O:BUZZ - Rises as inflammation drug shows promise in early trial nL4N3Y70RD

** Genprex Inc GNPX.O:BUZZ - Rises as diabetes gene therapy shows promise in animal tests nL4N3Y70RP

** Eli Lilly and Co LLY.N:

** Vertex Inc VRTX.O:

** Gilead Sciences Inc GILD.O:

** Regeneron Pharmaceuticals Inc REGN.O:BUZZ - Citi sees momentum in US pharma and biotech into 2026, updates ratings on top picks nL4N3Y70PF

** CoreWeave Inc CRWV.O:BUZZ - Gets 'hold' rating as Truist starts coverage; shares rise nL4N3Y70R4

** NovaBridge Biosciences NBP.O:BUZZ - Rises as cancer drug shows promise in early trial nL4N3Y70SV

** Palantir Technologies Inc PLTR.O:BUZZ - Truist initiates coverage of Palantir with 'buy' nL4N3Y70RN

** J.P.Morgan Chase & Co JPM.N:

** State Street Corp STT.N:

** Bank of New York Mellon Corp BK.N:

** Northern Trust Corp NTRS.O:BUZZ - Says market lag to boost US Q4 trust bank earnings; flags slower 2026 nL6N3Y70QC

** Newmont Corp NEM.N:

** Gold Fields Ltd GFI.N:

** Harmony Gold Mining Co Ltd HMY.N:

** AngloGold Ashanti PLC AU.N:

BUZZ - Gold miners rise as bullion gains on geopolitical risks and rate cut bets nL4N3Y7130

** American International Group Inc AIG.N:BUZZ - Shares fall as CEO Zaffino shifts to executive chair nL4N3Y70WV

** Accenture PLC ACN.N:BUZZ - Truist initiates Accenture coverage with 'buy' nL6N3Y70PW

** Intuit Inc INTU.O:BUZZ - Truist initiates coverage for Intuit with "buy" nL4N3Y70U5

** STAAR Surgical Co STAA.O:BUZZ - Plummets after ending planned $1.6 billion merger with Alcon nL6N3Y70S0

** Core Scientific Inc CORZ.O:BUZZ - Climbs as BTIG turns bullish following scrapped deal with CoreWeave nL6N3Y70RM

** Hesai Group HSAI.O:BUZZ - US-listed shares rise as Nvidia partners with Chinese firm for lidar sensors nL6N3Y70SJ

** $Bank of America Corp(BAC-N)$ BAC.N:

** Citizens Financial Group Inc CFG.N:

** PNC Financial Services Group Inc PNC.N:

** Truist Financial Corp TFC.N:BUZZ - AI benefits, commercial loan growth in focus for US big banks in 2026 - J.P. Morgan nL6N3Y70OD

** Terrestrial Energy Inc IMSR.O:BUZZ - Surges on deal with DOE for molten salt reactor pilot nL4N3Y70UH

** Hims & Hers Health Inc HIMS.N:BUZZ - TD Cowen cuts PT on Hims & Hers, citing valuation concerns nL4N3Y70TC

** Shake Shack Inc SHAK.N:BUZZ - Rises after Deutsche Bank upgrades stock nL6N3Y70SK

** Digital Realty Trust Inc DLR.N:

** Equinix Inc EQIX.O:BUZZ - Deutsche Bank initiates coverage of Digital Realty and Equinix with 'buy' nL4N3Y70WA

** Arrowhead Pharmaceuticals Inc ARWR.O:BUZZ - Rises on promising early-stage data for obesity treatments nL4N3Y70Y5

** iShares MSCI Saudi Arabia ETF KSA.N:BUZZ - At three-week high as kingdom to open markets to all investors nL4N3Y70XB

** EPAM Systems Inc EPAM.N:BUZZ - Truist launches coverage on EPAM Systems with 'hold' nL4N3Y70Z4

** Lockheed Martin Corp LMT.N:BUZZ - Soars after Defense Department deal to boost PAC-3 capacity nL6N3Y70UQ

** Uber Technologies Inc UBER.N:

** Lyft Inc LYFT.O:

** Grab Holdings Ltd GRAB.O:

** Nvidia Corp NVDA.O:BUZZ - Gain after Nvidia unveils Alpamayo tools nL6N3Y70VO

** TPG Inc TPG.O:BUZZ - Buys majority stake, commits $1 billion more in Lennar's platform; shares rise nL4N3Y711G

** Micron Technology Inc MU.O:

** Western Digital Corp WDC.O:

** Seagate Technology Holdings PLC STX.O:

** SanDisk Corp SNDK.O:BUZZ - Memory chipmakers soar as investors bet on price hikes from supply crunch nL6N3Y70VE

** United Airlines Holdings Inc UAL.O:

** Southwest Airlines Co LUV.N:

** American Airlines Group Inc AAL.O:

BUZZ - UBS lifts price targets on US airlines on bullish outlook hope nL4N3Y711H

** Brinker International Inc EAT.N:

** Dutch Bros Inc BROS.N:

** Chipotle Mexican Grill Inc CMG.N:

** Sweetgreen Inc SG.N:BUZZ - UBS sees improved US restaurant sector in 2026, Brinker up after upgrade nL6N3Y70V5

** CNX Resources Corp CNX.N:

** Expand Energy Corp EXE.O:

** Williams Companies Inc WMB.N:

** United States Natural Gas Fund LP UNG.N:

BUZZ - US natgas companies dip on forecasts for mild weather nL6N3Y70XR

** Builders FirstSource Inc BLDR.N:BUZZ - UBS cuts Builders FirstSource's PT amid higher mortgage rates nL6N3XO0WQ

** Johnson Controls International PLC JCI.N:

** Comfort Systems USA Inc FIX.N:

** Trane Technologies PLC TT.N:

** Vertiv Holdings Co VRT.N:BUZZ - Data center-related cooling stocks drop after Nvidia CEO hints at chiller-free future nL6N3Y70Y5

** First Guaranty Bancshares Inc FGBI.O:BUZZ - Extends strong start to 2026 nL6N3Y60OL

** Exxon Mobil Corp XOM.N:

** Chevron Corp CVX.N:

** ConocoPhillips COP.N:

** ProPetro Holding Corp PUMP.N:

BUZZ - Energy companies fall as crude prices drop amid supply concerns and Venezuelan uncertainty nL4N3Y7175

** Tesla Inc TSLA.O:

BUZZ - Down after Nvidia unveils open-source AI models for self-driving vehicles nL4N3Y7178

(Rajarshi Roy and Varun Sahay)

((Varun.sahay@thomsonreuters.com))