Summit Therapeutics and GSK Partner to Evaluate Ivonescimab and B7-H3 ADC in Solid Tumors

Reuters

01/12

<a href="https://laohu8.com/S/SMMT">Summit</a> <a href="https://laohu8.com/S/LENZ">Therapeutics</a> and GSK Partner to Evaluate Ivonescimab and B7-H3 ADC in Solid Tumors

Summit Therapeutics Inc. has announced a clinical trial collaboration with GSK to evaluate the combination of ivonescimab, Summit’s investigational PD-1/VEGF bispecific antibody, with GSK’s novel B7-H3-targeted antibody-drug conjugate, risvutatug rezetecan (GSK'227), across multiple solid tumor types, including small cell lung cancer. Under the agreement, Summit will provide ivonescimab for the study, while GSK will oversee clinical operations. Both companies will retain rights to their respective products, and the agreement is mutually non-exclusive. Patient dosing in the study is expected to begin in mid-2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Summit Therapeutics Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20260112976441) on January 12, 2026, and is solely responsible for the information contained therein.

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Under the agreement, Summit will provide ivonescimab for the study, while GSK will oversee clinical operations. Both companies will retain rights to their respective products, and the agreement is mutually non-exclusive. Patient dosing in the study is expected to begin in mid-2026.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<p>\n<i>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Summit Therapeutics Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20260112976441) on January 12, 2026, and is solely responsible for the information contained therein.</span></i>\n</p>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4139","symbol_name":"生物科技","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260112:nNDL6lyPNH:1","article_id":"2602955519","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2602955519","pubTimestamp":1768216517,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Summit Therapeutics Inc. has announced a clinical trial collaboration with GSK to evaluate the combination of ivonescimab, Summit’s investigational PD-1/VEGF bispecific antibody, with GSK’s novel B7-H3-targeted antibody-drug conjugate, risvutatug rezetecan , across multiple solid tumor types, including small cell lung cancer. 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