BioVie Inc. has released a corporate presentation detailing updates on its lead asset, bezisterim (formerly NE3107), a small molecule targeting TNF-α-mediated inflammation. Clinical trials have shown that bezisterim may reduce inflammation and insulin resistance, improve motor control in Parkinson’s disease patients, and support cognitive function in Alzheimer’s disease. The company is prioritizing the completion of a Phase 2b trial for Parkinson’s disease with topline data expected in the second quarter of 2026, and a Phase 2 exploratory trial for Long Covid, with topline readout anticipated in summer 2026. BioVie also highlighted plans for a Phase 3 ascites trial and a new Phase 3 Alzheimer’s trial, pending additional funding. Bezisterim has demonstrated the ability to cross the blood-brain barrier and has not shown safety issues in pre-clinical and Phase 2 trials. You can access the full presentation through the link below.

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